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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3zuk RDF Endopeptidase, peptidase family M13

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3zuk RDFEndopeptidase, peptidase family M13 / 1.115
4cth RDFNeprilysin / 0.907
4zr5 RDFNeprilysin / 0.844
3dwb RDFEndothelin-converting enzyme 1 3.4.24.71 0.793
3t8d UBVThermolysin 3.4.24.27 0.786
4d9w X32Thermolysin 3.4.24.27 0.784
4h57 0PJThermolysin 3.4.24.27 0.782
3t87 UBZThermolysin 3.4.24.27 0.778
3t74 UBYThermolysin 3.4.24.27 0.767
3t8c UBWThermolysin 3.4.24.27 0.763
6tmn 0PIThermolysin 3.4.24.27 0.751
4b52 RDFBacillolysin / 0.750
3t8h UBSThermolysin 3.4.24.27 0.748
3fvp UB2Thermolysin 3.4.24.27 0.724
4tmn 0PKThermolysin 3.4.24.27 0.723
1u4g HPIElastase 3.4.24.26 0.715
3fv4 1U4Thermolysin 3.4.24.27 0.714
1r1j OIRNeprilysin / 0.693
1r1i TI1Neprilysin / 0.651