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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3zc5 W9Z Hepatocyte growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3zc5 W9ZHepatocyte growth factor receptor 2.7.10.1 0.945
3zxz KRWHepatocyte growth factor receptor 2.7.10.1 0.863
3zbx 6XEHepatocyte growth factor receptor 2.7.10.1 0.817
4ap7 F47Hepatocyte growth factor receptor 2.7.10.1 0.738
4gg5 0J3Hepatocyte growth factor receptor 2.7.10.1 0.692
3zze 6XPHepatocyte growth factor receptor 2.7.10.1 0.670
4mf0 29ZTyrosine-protein kinase ITK/TSK 2.7.10.2 0.666
1zys 199Serine/threonine-protein kinase Chk1 2.7.11.1 0.656
4deg 0JJHepatocyte growth factor receptor 2.7.10.1 0.650