Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3wze BAX Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3wze BAXVascular endothelial growth factor receptor 2 2.7.10.1 1.288
4asd BAXVascular endothelial growth factor receptor 2 2.7.10.1 1.109
3vhe 42QVascular endothelial growth factor receptor 2 2.7.10.1 0.954
2rl5 2RLVascular endothelial growth factor receptor 2 2.7.10.1 0.885
3qri 919Tyrosine-protein kinase ABL1 2.7.10.2 0.855
2hzn KINTyrosine-protein kinase ABL1 2.7.10.2 0.845
5hi2 BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.844
3ugc 046Tyrosine-protein kinase JAK2 / 0.835
4u0i 0LIMast/stem cell growth factor receptor Kit 2.7.10.1 0.819
3gcs BAXMitogen-activated protein kinase 14 / 0.817
4ase AV9Vascular endothelial growth factor receptor 2 2.7.10.1 0.812
4agw NG7Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.808
3b8q 900Vascular endothelial growth factor receptor 2 2.7.10.1 0.803
2oh4 GIGVascular endothelial growth factor receptor 2 2.7.10.1 0.785
3b8r 887Vascular endothelial growth factor receptor 2 2.7.10.1 0.780
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.773
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.762
1uwh BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.729
4tyj 0LIFibroblast growth factor receptor 4 2.7.10.1 0.725
3gcq 1BUMitogen-activated protein kinase 14 / 0.723
1ywn LIFVascular endothelial growth factor receptor 2 2.7.10.1 0.721
3el8 PD5Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.719
4neu Q1AReceptor-interacting serine/threonine-protein kinase 1 2.7.11.1 0.714
4v01 0LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b / 0.712
3hv3 R49Mitogen-activated protein kinase 14 / 0.708
4at4 T6EBDNF/NT-3 growth factors receptor 2.7.10.1 0.708
3gi3 B10Mitogen-activated protein kinase 14 / 0.707
2puu G2GMitogen-activated protein kinase 14 / 0.705
4uxq 0LIFibroblast growth factor receptor 4 2.7.10.1 0.699
2c0o L2GTyrosine-protein kinase HCK 2.7.10.2 0.698
3dko IHZEphrin type-A receptor 7 2.7.10.1 0.697
3b2w 9NHTyrosine-protein kinase Lck 2.7.10.2 0.694
4o2z 046Mitogen-activated protein kinase / 0.694
1kv1 BMUMitogen-activated protein kinase 14 / 0.683
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.680
4twn B96Ephrin type-A receptor 3 2.7.10.1 0.680
3o8u BMUMitogen-activated protein kinase 14 / 0.679
4eyj N61Mitogen-activated protein kinase 13 2.7.11.24 0.673
3vs6 VSHTyrosine-protein kinase HCK 2.7.10.2 0.672
4equ G6ISerine/threonine-protein kinase 10 2.7.11.1 0.670
4f7n 0SVCyclin-dependent kinase 8 2.7.11.22 0.670
3o8t BMUMitogen-activated protein kinase 14 / 0.668
3lff Z83Mitogen-activated protein kinase 14 / 0.666
3oc1 BMUMitogen-activated protein kinase 14 / 0.665
2e2b 406Tyrosine-protein kinase ABL1 2.7.10.2 0.662
3uvr 06FMitogen-activated protein kinase 14 / 0.662
3p78 P78Mitogen-activated protein kinase 14 / 0.659
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.659
4i5h G17Mitogen-activated protein kinase 1 2.7.11.24 0.656
2c0i L1GTyrosine-protein kinase HCK 2.7.10.2 0.653
3el7 PD3Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.651
4f6w 0SSCyclin-dependent kinase 8 2.7.11.22 0.651