sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.236 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.229 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.124 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 1.116 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.111 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.093 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 1.018 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.008 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.995 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.986 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.986 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.967 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.945 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.944 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.944 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.936 | |
| 4kwh | NAP | Reductase homolog | / | 0.932 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.931 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.931 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.929 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.923 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.921 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.920 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.919 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.914 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.910 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.910 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.909 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.907 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.902 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.897 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.897 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.894 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.890 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.889 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.881 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.881 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.877 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.874 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.873 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.873 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.871 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.871 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.869 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.867 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.867 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.865 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.865 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.865 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.861 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.856 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.856 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.856 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.856 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.854 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.852 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.851 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.849 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.849 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.847 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.847 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.846 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.843 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.843 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.842 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.841 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.840 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.840 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.838 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.832 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.832 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.831 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.831 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.827 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.826 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.826 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.825 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.825 | |
| 3uce | NDP | Dehydrogenase | / | 0.823 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.822 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.821 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.819 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.818 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.817 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.816 | |
| 4qec | NAP | ElxO | / | 0.813 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.813 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.811 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.811 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.811 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.811 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.809 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.805 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.804 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.803 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.802 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.801 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.799 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.798 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.798 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.797 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.793 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.792 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.791 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.790 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.790 | |
| 4qed | NAP | ElxO | / | 0.790 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.789 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.787 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.786 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.786 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.784 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.783 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.779 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.777 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.774 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.773 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.772 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.772 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.772 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.770 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.770 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.769 | |
| 3mje | NDP | AmphB | / | 0.766 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.765 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.765 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.758 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.754 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.753 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.753 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.752 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.752 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.752 | |
| 1sny | NAP | LD36273p | / | 0.751 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.751 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.746 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.746 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.745 | |
| 4u7w | NDP | MxaA | / | 0.745 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.743 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.743 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.742 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.740 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.740 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.739 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.738 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.738 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.737 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.737 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.737 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.737 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.736 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.735 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.734 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.734 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.732 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.730 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.730 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.730 | |
| 3bmo | NAP | Pteridine reductase | / | 0.729 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.729 | |
| 3sju | NDP | Keto reductase | / | 0.729 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.726 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.725 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.725 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.725 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.723 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.721 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.721 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.720 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.719 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.717 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.717 | |
| 4hxy | NDP | Plm1 | / | 0.717 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.716 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.716 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.710 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.709 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.709 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.708 | |
| 5d2e | NAP | MlnE | / | 0.706 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.705 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.704 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.701 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.700 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.700 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.698 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.698 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.698 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.696 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.694 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.694 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.693 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.693 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.692 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.691 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.691 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.691 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.691 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.690 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.690 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.690 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.690 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.688 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.687 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.686 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.684 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.683 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.683 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.682 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.682 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 1iy8 | NAD | Levodione reductase | / | 0.681 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.681 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.681 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.681 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.680 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.680 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.679 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.678 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.676 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.676 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.675 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.673 | |
| 1hld | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.671 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.671 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.671 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.671 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.671 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.670 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.669 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.669 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.668 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.667 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.666 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.665 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.665 | |
| 2dph | NAD | Formaldehyde dismutase | / | 0.664 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.663 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.663 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.663 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.662 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.661 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.660 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.659 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.658 | |
| 4ng5 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.658 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.657 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.657 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.656 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.656 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.655 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.655 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.653 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.653 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.653 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.652 | |
| 3two | NDP | Mannitol dehydrogenase | / | 0.652 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.652 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.651 | |
| 4nfh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.651 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.650 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.650 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.650 |