sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.206 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.109 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.094 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.093 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 1.058 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.998 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.983 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.970 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.968 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.947 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.944 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.942 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.940 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.927 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.925 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.923 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.912 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.911 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.909 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.907 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.898 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.897 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.893 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.892 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.892 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.887 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.883 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.881 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.879 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.876 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.874 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.873 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.870 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.868 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.863 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.863 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.863 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.862 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.862 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.861 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.861 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.861 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.856 | |
| 4kwh | NAP | Reductase homolog | / | 0.856 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.853 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.852 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.851 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.850 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.849 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.848 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.847 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.847 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.846 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.845 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.842 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.842 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.840 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.837 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.836 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.833 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.831 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.831 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.829 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.828 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.827 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.827 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.821 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.820 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.818 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.817 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.817 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.816 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.810 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.808 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.807 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.806 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.805 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.805 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.804 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.802 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.801 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.801 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.799 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.799 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.796 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.794 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.794 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.794 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.792 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.791 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.790 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.788 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.787 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.780 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.780 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.780 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.777 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.777 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.777 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.775 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.774 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.773 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.771 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.771 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.771 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.767 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.765 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.764 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.764 | |
| 4u7w | NDP | MxaA | / | 0.764 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.763 | |
| 3mje | NDP | AmphB | / | 0.763 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.761 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.761 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.759 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.759 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.758 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.757 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.757 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.757 | |
| 4qec | NAP | ElxO | / | 0.757 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.756 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.755 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.755 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.754 | |
| 1sny | NAP | LD36273p | / | 0.753 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.751 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.750 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.749 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.749 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.748 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.748 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.748 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.747 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.746 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.746 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.746 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.744 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.744 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.744 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.743 | |
| 4qed | NAP | ElxO | / | 0.742 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.741 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.741 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.739 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.739 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.738 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.738 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.735 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.732 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.729 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.728 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.728 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.727 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.726 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.726 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.725 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.725 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.724 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.722 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.721 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.720 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.720 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.719 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.716 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.716 | |
| 5d2e | NAP | MlnE | / | 0.716 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.714 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.713 | |
| 1i36 | NAP | Conserved protein | / | 0.712 | |
| 3bmo | NAP | Pteridine reductase | / | 0.710 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.710 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.710 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.710 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.709 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.708 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.708 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.708 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.708 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.705 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.705 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.704 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.704 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.703 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.701 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.701 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.701 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.700 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.700 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.699 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.697 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.696 | |
| 3sju | NDP | Keto reductase | / | 0.696 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.694 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.693 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.691 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.690 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.689 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.689 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.688 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.686 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.684 | |
| 4hxy | NDP | Plm1 | / | 0.683 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.682 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.682 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.680 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.679 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.678 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.678 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.677 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.676 | |
| 3abi | NAD | Uncharacterized protein | / | 0.676 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.676 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.676 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.675 | |
| 1iy8 | NAD | Levodione reductase | / | 0.675 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.675 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.674 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.673 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.673 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.672 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.672 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.672 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.671 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.670 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.670 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.669 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.669 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.668 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.667 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.667 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.666 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.666 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.665 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.665 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.664 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.663 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.663 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.663 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.662 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.661 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.660 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.660 | |
| 1r37 | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.658 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.658 | |
| 3dtt | NAP | NADP oxidoreductase, coenzyme F420-dependent | / | 0.657 | |
| 4y0k | NAP | AntE | / | 0.657 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.656 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.656 | |
| 5kcp | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.656 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.655 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.655 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.655 | |
| 4y1b | NAP | AntE | / | 0.655 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.654 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.654 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.653 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.652 | |
| 1hdz | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.650 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.650 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.650 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.650 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.650 |