Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vnt 0JA Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 1.261
3vo3 0KFVascular endothelial growth factor receptor 2 2.7.10.1 0.836
4i5h G17Mitogen-activated protein kinase 1 2.7.11.24 0.728
4ckr DI1Epithelial discoidin domain-containing receptor 1 2.7.10.1 0.696
4agw NG7Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.692
3hng 8STVascular endothelial growth factor receptor 1 2.7.10.1 0.681
4asd BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.675
3bv2 P38Mitogen-activated protein kinase 14 / 0.674
3hv4 L51Mitogen-activated protein kinase 14 / 0.674
2e2b 406Tyrosine-protein kinase ABL1 2.7.10.2 0.671
2hiw 7MPTyrosine-protein kinase ABL1 2.7.10.2 0.668
3dtw A96Vascular endothelial growth factor receptor 2 2.7.10.1 0.668
1iep STITyrosine-protein kinase ABL1 2.7.10.2 0.667
4bkj STIEpithelial discoidin domain-containing receptor 1 2.7.10.1 0.667
3uvr 06FMitogen-activated protein kinase 14 / 0.662
2hyy STITyrosine-protein kinase ABL1 2.7.10.2 0.661
4l8m F46Mitogen-activated protein kinase 14 / 0.661
4qrc 0LIFibroblast growth factor receptor 4 2.7.10.1 0.660
3efl 706Vascular endothelial growth factor receptor 2 2.7.10.1 0.659
3wze BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.659
4fc0 0T2Serine/threonine-protein kinase B-raf 2.7.11.1 0.659
2qu5 276Vascular endothelial growth factor receptor 2 2.7.10.1 0.655
5hid B1ESerine/threonine-protein kinase B-raf 2.7.11.1 0.652