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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vbq 0F5 Serine/threonine-protein kinase pim-1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vbq 0F5Serine/threonine-protein kinase pim-1 2.7.11.1 1.031
2xj1 XJ1Serine/threonine-protein kinase pim-1 2.7.11.1 0.893
4enx Z20Serine/threonine-protein kinase pim-1 2.7.11.1 0.825
4eny J19Serine/threonine-protein kinase pim-1 2.7.11.1 0.779
2xj2 985Serine/threonine-protein kinase pim-1 2.7.11.1 0.739
3r04 UNQSerine/threonine-protein kinase pim-1 2.7.11.1 0.700
3bhm AB3Carbonyl reductase [NADPH] 1 1.1.1.184 0.693
5av4 GENDeath-associated protein kinase 1 2.7.11.1 0.658