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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3up3 XCA aceDAF-12

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3up3 XCAaceDAF-12 / 1.406
3up0 D7SaceDAF-12 / 0.861
3gki CLRNiemann-Pick C1 protein / 0.779
4bqu CLRJapanin / 0.755
4q0a 4OAVitamin D3 receptor A / 0.723
3w5q 3KLVitamin D3 receptor / 0.716
3gkj HC3Niemann-Pick C1 protein / 0.715
1ot7 CHCBile acid receptor / 0.704
3gyu DL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.697
5hyr ESTEstrogen receptor / 0.697
5l7d CLRSmoothened homolog / 0.691
4boe CLRJapanin / 0.685
2azz TCHPhospholipase A2, major isoenzyme 3.1.1.4 0.677
3q95 ESLEstrogen receptor / 0.663
3gyt DL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.661
2q7i TESAndrogen receptor / 0.660
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.654
1toj HCIAspartate aminotransferase 2.6.1.1 0.653
1y5r C0RCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.651
2hcd BIVVitamin D3 receptor A / 0.650