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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ukl FAD UDP-galactopyranose mutase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3ukl FADUDP-galactopyranose mutase / 1.342
3utg FDAUDP-galactopyranose mutase / 1.218
4u8k FDAUDP-galactopyranose mutase / 1.217
3uth FDAUDP-galactopyranose mutase / 1.180
4u8m FDAUDP-galactopyranose mutase / 1.170
4wx1 FDAUDP-galactopyranose mutase / 1.165
4u8l FDAUDP-galactopyranose mutase / 1.164
4gde FDAUDP-galactopyranose mutase / 1.158
3utf FDAUDP-galactopyranose mutase / 1.151
4u8i FDAUDP-galactopyranose mutase / 1.148
4u8p FDAUDP-galactopyranose mutase / 1.145
4u8o FDAUDP-galactopyranose mutase / 1.118
4u8j FDAUDP-galactopyranose mutase / 1.114
4u8n FDAUDP-galactopyranose mutase / 1.091
4dsg FADUncharacterized protein / 1.068
3ukf FDAUDP-galactopyranose mutase / 1.017
4dsh FDAUncharacterized protein / 0.979
3ukk FDAUDP-galactopyranose mutase / 0.975
3ukk FADUDP-galactopyranose mutase / 0.954
3uka FADUDP-galactopyranose mutase / 0.919
4gdc FADUDP-galactopyranose mutase / 0.861
5hhf FDAUDP-galactopyranose mutase / 0.853
1rsg FADPolyamine oxidase FMS1 / 0.804
3cn8 FADPolyamine oxidase FMS1 / 0.801
2y48 FADLysine-specific histone demethylase 1A 1 0.795
1f8r FADL-amino-acid oxidase 1.4.3.2 0.792
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.791
2jb1 FADL-amino acid oxidase / 0.791
2jae FADL-amino acid oxidase / 0.790
4fwf FADLysine-specific histone demethylase 1B 1 0.788
3kve FADL-amino-acid oxidase / 0.781
3we0 FADLysine 2-monooxygenase / 0.777
3cnd FADPolyamine oxidase FMS1 / 0.771
1f8s FADL-amino-acid oxidase 1.4.3.2 0.770
4gdp FADPolyamine oxidase FMS1 / 0.770
2xvi FADPutative flavin-containing monooxygenase / 0.769
2q7v FADThioredoxin reductase / 0.768
4gcm FADThioredoxin reductase 1.8.1.9 0.768
5g3t FDAFlavin-dependent L-tryptophan oxidase VioA / 0.768
1yy5 FADPolyamine oxidase FMS1 / 0.766
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.765
3cty FADProbable thioredoxin reductase / 0.765
2e1m FADL-glutamate oxidase / 0.763
4xbf FADLysine-specific histone demethylase 1A 1 0.763
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.761
2jb2 FADL-amino acid oxidase / 0.761
3r9u FADThioredoxin reductase / 0.761
2yg5 FADPutrescine oxidase / 0.758
3cnt FADPolyamine oxidase FMS1 / 0.758
3lov FADProtoporphyrinogen oxidase / 0.756
3bi2 FADPolyamine oxidase FMS1 / 0.753
4ech FADPolyamine oxidase FMS1 / 0.751
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.747
4gdd FADUDP-galactopyranose mutase / 0.747
2xlp FADPutative flavin-containing monooxygenase / 0.744
1tdo FADL-amino-acid oxidase 1.4.3.2 0.743
1tdk FADL-amino-acid oxidase 1.4.3.2 0.742
1z6l FADPolyamine oxidase FMS1 / 0.741
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.740
3kyb FADUDP-galactopyranose mutase 5.4.99.9 0.740
3bi5 FADPolyamine oxidase FMS1 / 0.738
4gur FADLysine-specific histone demethylase 1B 1 0.737
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.736
5l3d FADLysine-specific histone demethylase 1A 1 0.733
4hsu FADLysine-specific histone demethylase 1B 1 0.732
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.731
1jnz FADAdenylylsulfate reductase, subunit A (AprA) / 0.731
2yg4 FADPutrescine oxidase / 0.731
2ylx FADPhenylacetone monooxygenase 1.14.13.92 0.731
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.730
2iw5 FADLysine-specific histone demethylase 1A 1 0.730
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.730
4gus FADLysine-specific histone demethylase 1B 1 0.729
4rpg FADUDP-galactopyranose mutase 5.4.99.9 0.728
2dw4 FADLysine-specific histone demethylase 1A 1 0.727
2iid FADL-amino-acid oxidase 1.4.3.2 0.727
2cvj FADThioredoxin reductase related protein / 0.726
3kkj FADRenalase / 0.725
4gut FADLysine-specific histone demethylase 1B 1 0.724
3ute FADUDP-galactopyranose mutase / 0.721
4i58 FADCyclohexylamine Oxidase / 0.719
2xlr FADPutative flavin-containing monooxygenase / 0.718
4fwj FADLysine-specific histone demethylase 1B 1 0.718
1v0j FADUDP-galactopyranose mutase 5.4.99.9 0.717
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.717
2vq7 FADPutative flavin-containing monooxygenase / 0.716
2gvc FADThiol-specific monooxygenase 1.14.13 0.715
3qvr FADGlucose oxidase 1.1.3.4 0.715
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.714
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.714
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.714
2yls FADPhenylacetone monooxygenase 1.14.13.92 0.712
2xve FADPutative flavin-containing monooxygenase / 0.710
2xvf FADPutative flavin-containing monooxygenase / 0.710
2ylw FADPhenylacetone monooxygenase 1.14.13.92 0.710
3s5w FADL-ornithine N(5)-monooxygenase / 0.710
4guu FA9Lysine-specific histone demethylase 1B 1 0.710
1h81 FADPolyamine oxidase 1.5.3.14 0.709
1xpq FADPolyamine oxidase FMS1 / 0.709
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.708
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.708
2yg3 FADPutrescine oxidase / 0.708
3rha FDAPutrescine oxidase / 0.707
4wct FADFructosyl amine:oxygen oxidoreductase / 0.707
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.706
2fjd SFDAdenylylsulfate reductase, subunit A (AprA) / 0.705
3qj4 FADRenalase / 0.704
2xvh FADPutative flavin-containing monooxygenase / 0.703
3mj4 FADUDP-galactopyranose mutase / 0.703
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.703
3zdn FADMonoamine oxidase N 1.4.3.4 0.703
5br7 FADUDP-galactopyranose mutase / 0.703
3kpk FADSulfide-quinone reductase / 0.702
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.701
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.701
2c4c FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.701
3lsm SFDPyranose 2-oxidase / 0.701
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.698
3k7t FAD6-hydroxy-L-nicotine oxidase / 0.698
2yg6 FADPutrescine oxidase / 0.697
4fx9 FADCoenzyme A disulfide reductase 1.8.1.14 0.697
5g3s FDAFlavin-dependent L-tryptophan oxidase VioA / 0.697
1h83 FADPolyamine oxidase 1.5.3.14 0.696
1y56 FAD382aa long hypothetical sarcosine oxidase / 0.696
3hdy FADUDP-galactopyranose mutase / 0.696
4rsl FADFructosyl peptide oxidase / 0.696
2xls FADPutative flavin-containing monooxygenase / 0.695
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.694
3uoy FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.694
4mo2 FDAUDP-galactopyranose mutase / 0.694
1reo FADL-amino-acid oxidase 1.4.3.2 0.693
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.693
1jnr FADAdenylylsulfate reductase, subunit A (AprA) / 0.692
4d04 FADPhenylacetone monooxygenase 1.14.13.92 0.692
4eqw FADCoenzyme A disulfide reductase / 0.691
1tdf FADThioredoxin reductase 1.8.1.9 0.690
2ywl FADThioredoxin reductase related protein / 0.690
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.689
3ict FADCoenzyme A disulfide reductase / 0.689
4fwe FADLysine-specific histone demethylase 1B 1 0.689
4tm3 FADKtzI / 0.689
4h4u FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.688
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.687
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.686
2bi8 FADUDP-galactopyranose mutase 5.4.99.9 0.686
3ka7 FADPutative oxidoreductase / 0.685
3nta FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.684
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.684
4cnk FADL-amino acid oxidase / 0.683
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.683
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.683
2b9x FADPutative aminooxidase / 0.682
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.682
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.681
2h94 FADLysine-specific histone demethylase 1A 1 0.681
2isk FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.681
3hdy FDAUDP-galactopyranose mutase / 0.681
3kpf FADPolyamine oxidase 1.5.3.14 0.681
2bac FADPutative aminooxidase / 0.680
2vou FAD2,6-dihydroxypyridine 3-monooxygenase 1.14.13.10 0.680
3cgc FADCoenzyme A disulfide reductase / 0.680
4h4x FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.680
3int FDAUDP-galactopyranose mutase 5.4.99.9 0.679
4nzh FADL-ornithine N(5)-monooxygenase / 0.679
5cku FADL-ornithine N(5)-monooxygenase / 0.679
1cf3 FADGlucose oxidase 1.1.3.4 0.676
2ign FADPyranose 2-oxidase / 0.676
2igo FADPyranose 2-oxidase / 0.675
2rgj FADFlavin-containing monooxygenase / 0.675
3vqr FADPutative oxidoreductase / 0.675
5er0 FADUncharacterized NAD(FAD)-dependent dehydrogenase / 0.675
1trb FADThioredoxin reductase 1.8.1.9 0.674
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.674
2hko FADLysine-specific histone demethylase 1A 1 0.674
3nlc FADUncharacterized protein / 0.674
1gal FADGlucose oxidase 1.1.3.4 0.673
1tde FADThioredoxin reductase 1.8.1.9 0.673
2vqb FADPutative flavin-containing monooxygenase / 0.673
3awi FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 1.5 0.673
3bg7 FADPyranose 2-oxidase / 0.673
4mok FADPyranose 2-oxidase / 0.673
1sez FADProtoporphyrinogen oxidase, mitochondrial 1.3.3.4 0.672
3he3 FADUDP-galactopyranose mutase / 0.672
3lsi FADPyranose 2-oxidase / 0.672
4jnq FDAThioredoxin reductase / 0.672
1f8w FADNADH peroxidase 1.11.1.1 0.671
4rpj FADUDP-galactopyranose mutase 5.4.99.9 0.671
4z26 FADPutative GMC-type oxidoreductase R135 1 0.671
2b9y FADPutative aminooxidase / 0.670
4emw FADCoenzyme A disulfide reductase / 0.670
4j36 FADKynurenine 3-monooxygenase / 0.670
4mo2 FADUDP-galactopyranose mutase / 0.670
4ynt FDAGlucose oxidase, putative / 0.670
1npx FADNADH peroxidase 1.11.1.1 0.669
2gv8 FADThiol-specific monooxygenase 1.14.13 0.669
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.669
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.669
2vvl FADMonoamine oxidase N 1.4.3.4 0.668
3ish FADThioredoxin reductase 1.8.1.9 0.668
4up3 FADThioredoxin reductase / 0.668
1tdn FADL-amino-acid oxidase 1.4.3.2 0.667
2ym1 FADPhenylacetone monooxygenase 1.14.13.92 0.667
3cgb FADCoenzyme A disulfide reductase / 0.667
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.667
4jdr FADDihydrolipoyl dehydrogenase 1.8.1.4 0.667
4uir FADOleate hydratase 4.2.1.53 0.667
3nn6 FB06-hydroxy-L-nicotine oxidase / 0.666
4c5o FADPutative monooxygenase / 0.666
3atr FDAConserved Archaeal protein / 0.665
3gsi FADDimethylglycine oxidase 1.5.3.10 0.665
3t2y FADSulfide-quinone reductase / 0.664
2gqw FADFerredoxin reductase / 0.663
3cgd FADCoenzyme A disulfide reductase / 0.663
4j33 FADKynurenine 3-monooxygenase / 0.663
3f6s FMNFlavodoxin / 0.662
4b63 FADL-ornithine N(5)-monooxygenase / 0.662
4eqs FADCoenzyme A disulfide reductase / 0.662
2yg7 FADPutrescine oxidase / 0.661
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.661
2apg FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.660
2ylt FADPhenylacetone monooxygenase 1.14.13.92 0.660
3icr FADCoenzyme A disulfide reductase / 0.660
3m13 FADMonomeric sarcosine oxidase 1.5.3.1 0.660
1zx9 FADMercuric reductase 1.16.1.1 0.659
3cge FADCoenzyme A disulfide reductase / 0.659
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.658
1qo8 FADFumarate reductase flavoprotein subunit / 0.657
2eq7 FADDihydrolipoyl dehydrogenase / 0.657
2oa1 FADFlavin-dependent tryptophan halogenase RebH 1.14.19.9 0.657
3ada NADSubunit alpha of sarocosine oxidase / 0.657
4usr FADMonooxygenase / 0.657
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.656
2jkc FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.656
4b69 FADL-ornithine N(5)-monooxygenase / 0.656
4cnj FADL-amino acid oxidase / 0.656
4mih FADPyranose 2-oxidase 1.1.3.10 0.656
1jeh FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.655
4ysh FADGlycine oxidase / 0.655
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 0.654
3cuk FADD-amino-acid oxidase 1.4.3.3 0.654
3f8d FADNADH oxidase/thioredoxin reductase / 0.654
4fk1 FADPutative thioredoxin reductase / 0.654
4yac NAIC alpha-dehydrogenase / 0.654
2bab FADPutative aminooxidase / 0.653
2f5z FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.653
2oal FADFlavin-dependent tryptophan halogenase RebH 1.14.19.9 0.653
3b6d FAECholesterol oxidase 1.1.3.6 0.653
3c4a FADProtodeoxyviolaceinate monooxygenase 1 0.653
3k30 ADPHistamine dehydrogenase / 0.653
5fs9 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.653
4eqx FADCoenzyme A disulfide reductase / 0.652
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.651
3k4c FADPyranose 2-oxidase / 0.651
3rnm FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.651
4yjd FADD-amino-acid oxidase 1.4.3.3 0.651
1geu FADGlutathione reductase 1.8.1.7 0.650
5hxw FADL-amino acid deaminase / 0.650
5j60 FADThioredoxin reductase / 0.650