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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3toz NAD Shikimate dehydrogenase (NADP(+))

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3toz NADShikimate dehydrogenase (NADP(+)) / 1.044
3tnl NADShikimate dehydrogenase (NADP(+)) / 0.916
3t4e NADQuinate/shikimate dehydrogenase / 0.881
1npd NADQuinate/shikimate dehydrogenase / 0.848
1vi2 NADQuinate/shikimate dehydrogenase / 0.812
1o9b NAIQuinate/shikimate dehydrogenase / 0.730
1nyt NAPShikimate dehydrogenase (NADP(+)) / 0.719
4k28 NADShikimate dehydrogenase family protein / 0.717
4xgi NADGlutamate dehydrogenase / 0.682
2hk9 ATRShikimate dehydrogenase (NADP(+)) / 0.681
1do8 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.680
3zhb NAPPutative dehydrogenase / 0.680
2hk9 NAPShikimate dehydrogenase (NADP(+)) / 0.679
2ev9 NAPShikimate dehydrogenase (NADP(+)) / 0.678
2vq3 NAPMetalloreductase STEAP3 / 0.671
2cy0 NAPShikimate dehydrogenase (NADP(+)) / 0.670
3anm NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.664
3phi NDPShikimate dehydrogenase (NADP(+)) / 0.664
1ee9 NADMethylenetetrahydrofolate dehydrogenase [NAD(+)] 1.5.1.15 0.663
2ph5 NADHomospermidine synthase / 0.659
5ijz NAPNADP-specific glutamate dehydrogenase 1.4.1.4 0.658
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.654
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.652
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.652
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.651
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.650