Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3t9d ANP Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3t9d ANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 1.230
3t9a ANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 1.148
4nzo ANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 1.068
4q4c ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.974
3t54 ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.959
3t9e ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.945
3t99 ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.925
3t9f ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.917
1lp4 ANPCasein kinase II subunit alpha 2.7.11.1 0.838
3x2w ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.837
3x2v ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.819
4dg3 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.804
4c5c ATPD-alanine--D-alanine ligase B 6.3.2.4 0.802
1z2p ACPInositol-tetrakisphosphate 1-kinase 2.7.1.134 0.787
4iai ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.786
1o6k ANPRAC-beta serine/threonine-protein kinase 2.7.11.1 0.785
1m0w ANPGlutathione synthetase 6.3.2.3 0.776
2p0a ANPSynapsin-3 / 0.772
1daw ANPCasein kinase II subunit alpha 2.7.11.1 0.771
3fhi ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.770
4c5b ADPD-alanine--D-alanine ligase B 6.3.2.4 0.755
4xw6 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.755
1l8t ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.752
2io7 ANPBifunctional glutathionylspermidine synthetase/amidase / 0.752
3fjq ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.752
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.747
2phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.746
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.745
3gu5 ANPDeath-associated protein kinase 1 2.7.11.1 0.735
3tw6 ADPPyruvate carboxylase / 0.732
4ej7 ATPAminoglycoside 3'-phosphotransferase AphA1-IAB / 0.732
4i3z ADPCyclin-dependent kinase 2 2.7.11.22 0.731
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.731
1j7u ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.729
3rv4 ADPBiotin carboxylase 6.3.4.14 0.728
4wb6 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.727
1cdk ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.726
3vpc ADPGlutamate--LysW ligase ArgX 6.3.2 0.723
4gvj ADPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.723
2io9 ADPBifunctional glutathionylspermidine synthetase/amidase / 0.722
4dh7 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.721
4ysj ADPCalmodulin-like domain protein kinase / 0.719
3i12 ADPD-alanine--D-alanine ligase A 6.3.2.4 0.718
3idb ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.717
4oav ACP2-5A-dependent ribonuclease 3.1.26 0.717
1phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.716
4ffl ADPUncharacterized protein / 0.716
5e92 ANPTGF-beta receptor type-2 2.7.11.30 0.716
3dnt ATPSerine/threonine-protein kinase toxin HipA / 0.715
1day GNPCasein kinase II subunit alpha 2.7.11.1 0.714
1a9x ADPCarbamoyl-phosphate synthase large chain / 0.711
4ffr ATPUncharacterized protein / 0.711
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.711
1jkk ANPDeath-associated protein kinase 1 2.7.11.1 0.708
4fi1 ATPCasein kinase II subunit alpha 2.7.11.1 0.708
4iac ACPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.706
1j7l ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.703
5c1o ANPD-alanine--D-alanine ligase / 0.703
3tm0 ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.702
4nm7 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.702
2pup ADPMethylthioribose kinase 2.7.1.100 0.700
2vqd AP2Biotin carboxylase 6.3.4.14 0.699
2io8 ADPBifunctional glutathionylspermidine synthetase/amidase / 0.695
5iqh GNPBifunctional AAC/APH 2.3.1 0.694
4qpm ADPMitotic checkpoint serine/threonine-protein kinase BUB1 2.7.11.1 0.693
5bpf ADPD-alanine--D-alanine ligase / 0.693
5iqb GNPBifunctional AAC/APH 2.3.1 0.693
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.692
3idc ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.691
3vpb ADPGlutamate--LysW ligase ArgX 6.3.2 0.689
4x6r ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.689
4dee ADPAurora kinase A 2.7.11.1 0.688
2zdg ADPD-alanine--D-alanine ligase / 0.687
3q5i ANPProtein kinase, putative / 0.686
4lfi GNPCasein kinase II subunit alpha 2.7.11.1 0.686
1aux AGSSynapsin-1 / 0.685
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.685
3w8q AGSDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.685
1dv2 ATPBiotin carboxylase 6.3.4.14 0.684
1t36 ADPCarbamoyl-phosphate synthase large chain / 0.684
1pk8 ATPSynapsin-1 / 0.683
3c4z ADPRhodopsin kinase / 0.683
2hgs ADPGlutathione synthetase 6.3.2.3 0.681
1ss9 UPFLgtC / 0.679
4wh2 ADPN-acetylhexosamine 1-kinase 2.7.1.162 0.679
3gu4 ANPDeath-associated protein kinase 1 2.7.11.1 0.678
3lmi ATPMyosin heavy chain kinase A 2.7.11.7 0.678
4nm5 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.677
5byl GCPBifunctional AAC/APH 2.3.1 0.677
2qcs ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.676
4o1p ANPRibonuclease L / 0.676
3akk ADPSerine/threonine-protein kinase CtkA 2.7.11.1 0.675
3r5f ATPD-alanine--D-alanine ligase / 0.675
4ii5 ADPCyclin-dependent kinase 2 2.7.11.22 0.674
4ekk ANPRAC-alpha serine/threonine-protein kinase 2.7.11.1 0.672
4utd ACPAurora kinase A 2.7.11.1 0.672
5cvh ADPCasein kinase II subunit alpha 2.7.11.1 0.671
4dn5 AGSMitogen-activated protein kinase kinase kinase 14 2.7.11.25 0.670
2j9g ADPBiotin carboxylase 6.3.4.14 0.669
3eth ATPN5-carboxyaminoimidazole ribonucleotide synthase / 0.669
3tpt ADPSerine/threonine-protein kinase toxin HipA / 0.669
3gub GUBDeath-associated protein kinase 1 2.7.11.1 0.667
2b9f ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.666
3x2u ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
2j9g ANPBiotin carboxylase 6.3.4.14 0.665
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.663
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.663
4f99 ADPCell division cycle 7-related protein kinase 2.7.11.1 0.663
2bkk ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.662
4uxx ACPDiacylglycerol kinase 2.7.1.107 0.661
3wo1 ADPAlanine--anticapsin ligase / 0.660
4f9a ADPCell division cycle 7-related protein kinase 2.7.11.1 0.659
3wnz ADPAlanine--anticapsin ligase / 0.658
4s33 ANPMitogen-activated protein kinase 1 2.7.11.24 0.657
2b0q ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.656
2qo7 ANPEphrin type-A receptor 3 2.7.10.1 0.656
3c4x ATPRhodopsin kinase / 0.656
4wh3 ATPN-acetylhexosamine 1-kinase 2.7.1.162 0.656
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.655
3wo0 ADPAlanine--anticapsin ligase / 0.655
4fu0 ADPD-alanine--D-alanine ligase / 0.655
2oap ANPType II secretion system protein (GspE-2) / 0.654
2rio ADPSerine/threonine-protein kinase/endoribonuclease IRE1 2.7.11.1 0.654
4mam A12N5-carboxyaminoimidazole ribonucleotide synthase / 0.654
3q1k ADPD-alanine--D-alanine ligase A 6.3.2.4 0.652
1px2 ATPSynapsin-1 / 0.651
3qc9 ADPRhodopsin kinase / 0.651
2j0l ANPFocal adhesion kinase 1 2.7.10.2 0.650
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.650
4bgb ADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases / 0.650