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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3svg ODR Bromodomain-containing protein 4

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3svg ODRBromodomain-containing protein 4 / 0.911
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.744
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4e5l DBHPolymerase acidic protein / 0.744
4qzs JQ1Bromodomain-containing protein 4 / 0.705
4alh A9PBromodomain-containing protein 2 / 0.686
4a9n A9NBromodomain-containing protein 2 / 0.684
4j0r 1H2Bromodomain-containing protein 4 / 0.684
4flp JQ1Bromodomain testis-specific protein / 0.681
4lr6 1XABromodomain-containing protein 4 / 0.679
4j0s 1H3Bromodomain-containing protein 4 / 0.676
4gpj 0Q1Bromodomain-containing protein 4 / 0.672
4f3i 0S6Bromodomain-containing protein 4 / 0.671
4a9l P9LBromodomain-containing protein 4 / 0.668
4bw1 S5BBromodomain-containing protein 4 / 0.663
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4bw2 UTHBromodomain-containing protein 4 / 0.658
4lrg 1XBBromodomain-containing protein 4 / 0.656