Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3srw Q27 Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3srw Q27Dihydrofolate reductase 1.5.1.3 1.152
3sru Q26Dihydrofolate reductase 1.5.1.3 0.839
3srr Q20Dihydrofolate reductase 1.5.1.3 0.717
3sqy Q11Dihydrofolate reductase 1.5.1.3 0.704
3srs M23Dihydrofolate reductase 1.5.1.3 0.701
3frf XCFDihydrofolate reductase 1.5.1.3 0.681
4dfr MTXDihydrofolate reductase 1.5.1.3 0.664
3fre TOPDihydrofolate reductase 1.5.1.3 0.657
3fra I2HDihydrofolate reductase 1.5.1.3 0.652