Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rv3 ADP Biotin carboxylase 6.3.4.14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3rv3 ADPBiotin carboxylase 6.3.4.14 0.960
3rup ADPBiotin carboxylase 6.3.4.14 0.913
1wur 8DGGTP cyclohydrolase 1 / 0.691
4to3 DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.689
4qfy DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.675
1f06 NDPMeso-diaminopimelate D-dehydrogenase 1.4.1.16 0.674
4rnx FMNNADPH dehydrogenase 1 1.6.99.1 0.672
3hgs FMN12-oxophytodienoate reductase 3 1.3.1.42 0.667
3zy3 GDPGDP-fucose protein O-fucosyltransferase 1 2.4.1.221 0.665
1h5q NAPNADP-dependent mannitol dehydrogenase 1.1.1.138 0.661
1mez GDPAdenylosuccinate synthetase isozyme 1 / 0.660
4l4x NDPAmphI / 0.655
1dgb NDPCatalase 1.11.1.6 0.652
2rbe NDPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.651