Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ru0 SFG Histone-lysine N-methyltransferase SMYD3 2.1.1.43

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3ru0 SFGHistone-lysine N-methyltransferase SMYD3 2.1.1.43 1.012
3pdn SFGHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.982
5hq8 SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.931
3qwp SAMHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.912
3oxf SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.882
3tg4 SAMN-lysine methyltransferase SMYD2 / 0.854
4o6f SAHN-lysine methyltransferase SMYD2 / 0.854
5ex0 SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.834
3n71 SFGHistone-lysine N-methyltransferase Smyd1 / 0.795
4j83 SAMHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.790
2h21 SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.789
3m53 SAHHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.784
4h12 SAHHistone-lysine N-methyltransferase SETD2 2.1.1.43 0.770
1n6c SAMHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.759
1mlv SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.758
3rib SAHN-lysine methyltransferase SMYD2 / 0.755
3cbp SFGHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.745
2rfi SAHHistone-lysine N-methyltransferase EHMT1 / 0.743
1ozv SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.742
5jhn SAMHistone-lysine N-methyltransferase EHMT2 / 0.741
5jin SAMHistone-lysine N-methyltransferase EHMT2 / 0.740
5czy SAMEukaryotic huntingtin interacting protein B / 0.739
4o30 SAHProbable Histone-lysine N-methyltransferase ATXR5 2.1.1.43 0.736
3fpd SAHHistone-lysine N-methyltransferase EHMT1 / 0.735
2bqz SAHN-lysine methyltransferase KMT5A / 0.730
1p0y SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.726
2h23 SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.726
2h2j SFGRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.725
5jj0 SAMHistone-lysine N-methyltransferase EHMT2 / 0.725
4qen SAHHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 2.1.1.43 0.708
3kmt SAHHistone H3K27 methylase / 0.706
2o8j SAHHistone-lysine N-methyltransferase EHMT2 / 0.693
3swc SAHHistone-lysine N-methyltransferase EHMT1 / 0.692
3vv0 KH3Histone-lysine N-methyltransferase SETD7 2.1.1.43 0.690
3mo0 SAHHistone-lysine N-methyltransferase EHMT1 / 0.689
3vuz K15Histone-lysine N-methyltransferase SETD7 2.1.1.43 0.682
3ooi SAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 2.1.1.43 0.679
2igq SAHHistone-lysine N-methyltransferase EHMT1 / 0.672
4z4p SAHHistone-lysine N-methyltransferase 2D 2.1.1.43 0.667
5hyn SAHHistone-lysine N-methyltransferase EZH2 2.1.1.43 0.657
1v25 ANPLong-chain-fatty-acid--CoA ligase 6.2.1.3 0.653