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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rin I2O Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3rin I2OMitogen-activated protein kinase 14 / 1.358
3gfe P37Mitogen-activated protein kinase 14 / 0.873
3e93 19BMitogen-activated protein kinase 14 / 0.859
3u8w 09JMitogen-activated protein kinase 14 / 0.856
3itz P66Mitogen-activated protein kinase 14 / 0.831
4kiq 1RAMitogen-activated protein kinase 14 / 0.826
3e92 G6AMitogen-activated protein kinase 14 / 0.816
3fkl FKLMitogen-activated protein kinase 14 / 0.809
3dt1 P40Mitogen-activated protein kinase 14 / 0.799
3s4q NK0Mitogen-activated protein kinase 14 / 0.792
3d7z GK5Mitogen-activated protein kinase 14 / 0.784
3iph G11Mitogen-activated protein kinase 14 / 0.781
2zb0 GK3Mitogen-activated protein kinase 14 / 0.780
4kin 1M8Mitogen-activated protein kinase 14 / 0.775
4aa5 NQBMitogen-activated protein kinase 14 / 0.764
3ds6 A17Mitogen-activated protein kinase 14 / 0.763
4kip 1R9Mitogen-activated protein kinase 14 / 0.730
2rg5 279Mitogen-activated protein kinase 14 / 0.711
2yix YIXMitogen-activated protein kinase 14 / 0.710
2zb1 GK4Mitogen-activated protein kinase 14 / 0.708
2og8 1N8Tyrosine-protein kinase Lck 2.7.10.2 0.700
3l8x N4DMitogen-activated protein kinase 14 / 0.698
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.688
2bal PQAMitogen-activated protein kinase 14 / 0.683
4i5h G17Mitogen-activated protein kinase 1 2.7.11.24 0.681
1w83 L11Mitogen-activated protein kinase 14 / 0.680
4v01 0LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b / 0.678
3d83 GK6Mitogen-activated protein kinase 14 / 0.677
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.675
2xyu Q9GEphrin type-A receptor 4 2.7.10.1 0.673
4uxq 0LIFibroblast growth factor receptor 4 2.7.10.1 0.672
4aa0 AA0Mitogen-activated protein kinase 14 / 0.668
3hv5 R24Mitogen-activated protein kinase 14 / 0.663
3mvl 38PMitogen-activated protein kinase 14 / 0.663
3fmm XI2Mitogen-activated protein kinase 14 / 0.661
3aqa BYHBromodomain-containing protein 2 / 0.657
3gc8 B45Mitogen-activated protein kinase 11 2.7.11.24 0.657
2zla VDBVitamin D3 receptor / 0.654
3nnu EDBMitogen-activated protein kinase 14 / 0.650