Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rg9 WRA Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3rg9 WRABifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 1.145
1j3i WRABifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.889
3inv C50Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.761
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3um8 1CYBifunctional dihydrofolate reductase-thymidylate synthase / 0.700
1j3k WRABifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.683
1kms LIHDihydrofolate reductase 1.5.1.3 0.679
3um6 1CYBifunctional dihydrofolate reductase-thymidylate synthase / 0.668
4e5f 0N7Polymerase acidic protein / 0.660