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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rbv NAP Sugar 3-ketoreductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3rbv NAPSugar 3-ketoreductase / 1.070
1h6c NDPGlucose--fructose oxidoreductase 1.1.99.28 0.722
1ryd NDPGlucose--fructose oxidoreductase 1.1.99.28 0.721
1rye NDPGlucose--fructose oxidoreductase 1.1.99.28 0.706
1h6a NDPGlucose--fructose oxidoreductase 1.1.99.28 0.703
3wbf NAPMeso-diaminopimelate D-dehydrogenase / 0.700
5a02 NAPGlucose-fructose oxidoreductase / 0.698
1h6d NDPGlucose--fructose oxidoreductase 1.1.99.28 0.692
1ofg NDPGlucose--fructose oxidoreductase 1.1.99.28 0.681
4koa NDP1,5-anhydro-D-fructose reductase 1.1.1.292 0.681
1zh8 NAPUncharacterized protein / 0.678
2glx NDP1,5-anhydro-D-fructose reductase / 0.677
2f1k NAPPrephenate dehydrogenase / 0.675
5ein NAP[LysW]-L-2-aminoadipate 6-phosphate reductase / 0.663
4l8v NAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.660
2czc NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.59 0.652
2vq3 NAPMetalloreductase STEAP3 / 0.651
3wbb NAPMeso-diaminopimelate D-dehydrogenase / 0.651