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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rbm B73 Farnesyl pyrophosphate synthase, putative

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3rbm B73Farnesyl pyrophosphate synthase, putative / 1.431
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.794
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.793
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.791
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.788
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.785
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.783
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.782
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.776
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.775
2i19 1BYFarnesyl pyrophosphate synthase / 0.739
3ryw K9HFarnesyl pyrophosphate synthase, putative / 0.738
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.722
3icz PB6Farnesyl pyrophosphate synthase / 0.718
3krf DSTGeranyl diphosphate synthase large subunit / 0.713
2e8w IPEGeranylgeranyl pyrophosphate synthase / 0.705
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.702
2o1o RISPutative farnesyl pyrophosphate synthase / 0.692
3dyh 721Farnesyl pyrophosphate synthase / 0.690
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.689
3kmw ATPIntegrin-linked protein kinase 2.7.11.1 0.682
4to0 DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.680
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.674
4tnq TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.674
1a5u ATPPyruvate kinase PKM 2.7.1.40 0.669
2py7 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.668
3au2 DGTDNA polymerase beta family (X family) / 0.666
5erm 210Fusicoccadiene synthase 4.2.3.43 0.664
2z4z SC0Geranylgeranyl pyrophosphate synthase / 0.659
4jvj 1MVFarnesyl pyrophosphate synthase 2.5.1.10 0.656
2z4y 252Geranylgeranyl pyrophosphate synthase / 0.655
3egt 722Farnesyl pyrophosphate synthase / 0.654
4bzb DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.652
1p52 ADPArginine kinase 2.7.3.3 0.651
4fw4 3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.651
4dwb 0M7Farnesyl pyrophosphate synthase / 0.650