Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 |
PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
---|---|---|---|---|---|
3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.146 | |
3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.056 | |
4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.015 | |
3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.000 | |
2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.975 | |
3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.973 | |
4la1 | FAD | Thioredoxin glutathione reductase | / | 0.970 | |
2x8h | FAD | Thioredoxin glutathione reductase | / | 0.953 | |
3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.940 | |
2x8g | FAD | Thioredoxin glutathione reductase | / | 0.937 | |
2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.932 | |
4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.930 | |
2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.928 | |
2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.921 | |
1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.920 | |
1get | FAD | Glutathione reductase | 1.8.1.7 | 0.908 | |
2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.907 | |
1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.905 | |
2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.902 | |
2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.899 | |
3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.894 | |
1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.893 | |
1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.884 | |
2wow | FAD | Trypanothione reductase | / | 0.880 | |
1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.878 | |
3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.876 | |
2v6o | FAD | Thioredoxin glutathione reductase | / | 0.875 | |
2wp5 | FAD | Trypanothione reductase | / | 0.874 | |
1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.871 | |
1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.865 | |
2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.863 | |
4nev | FAD | Trypanothione reductase | / | 0.863 | |
3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.859 | |
1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.856 | |
2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.854 | |
2r9z | FAD | Glutathione amide reductase | / | 0.854 | |
2w0h | FAD | Trypanothione reductase | / | 0.851 | |
3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.850 | |
3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.850 | |
1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.849 | |
1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.849 | |
2rab | FAD | Glutathione amide reductase | / | 0.848 | |
3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.840 | |
4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.831 | |
1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.830 | |
3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.830 | |
1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.827 | |
1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.827 | |
1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.826 | |
1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.823 | |
1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.821 | |
2jk6 | FAD | Trypanothione reductase | / | 0.821 | |
1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.819 | |
1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.814 | |
2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.814 | |
1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.806 | |
4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.806 | |
2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.805 | |
4dna | FAD | Probable glutathione reductase | / | 0.805 | |
4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.802 | |
2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.799 | |
1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.797 | |
1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.797 | |
3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.794 | |
1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.790 | |
3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.790 | |
2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.787 | |
4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.776 | |
1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.773 | |
4nte | FAD | DepH | / | 0.773 | |
2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.765 | |
1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.763 | |
4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.763 | |
4ntc | FAD | Thioredoxin reductase gliT | / | 0.762 | |
2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.760 | |
1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.757 | |
1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.756 | |
2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.756 | |
1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.750 | |
2zbw | FAD | Ferredoxin--NADP reductase | / | 0.750 | |
4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.750 | |
1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.749 | |
3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.748 | |
4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.747 | |
3fbs | FAD | Oxidoreductase | / | 0.746 | |
3cty | FAD | Probable thioredoxin reductase | / | 0.744 | |
2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.742 | |
1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.740 | |
1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.736 | |
1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.735 | |
4ccr | FAD | Thioredoxin reductase | / | 0.735 | |
1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.734 | |
4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.730 | |
3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.728 | |
2qa1 | FAD | PgaE | / | 0.726 | |
4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.725 | |
1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.724 | |
3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.724 | |
3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.724 | |
4cbq | FAD | Thioredoxin reductase | / | 0.724 | |
3ict | FAD | Coenzyme A disulfide reductase | / | 0.722 | |
1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.721 | |
1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.720 | |
2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.720 | |
3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.720 | |
2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.719 | |
1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.718 | |
1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.718 | |
2bac | FAD | Putative aminooxidase | / | 0.716 | |
4a65 | FAD | Thioredoxin reductase | / | 0.716 | |
4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.715 | |
4bk3 | FAD | Probable salicylate monooxygenase | / | 0.714 | |
3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.713 | |
4a5l | FAD | Thioredoxin reductase | / | 0.713 | |
4ccq | FAD | Thioredoxin reductase | / | 0.713 | |
4hb9 | FAD | Uncharacterized protein | / | 0.712 | |
4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.712 | |
1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.710 | |
1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.710 | |
1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.710 | |
1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.709 | |
4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.709 | |
4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.709 | |
1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.708 | |
1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.708 | |
1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.708 | |
4up3 | FAD | Thioredoxin reductase | / | 0.708 | |
4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.708 | |
2b9w | FAD | Putative aminooxidase | / | 0.707 | |
2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.707 | |
3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.707 | |
4jnq | FDA | Thioredoxin reductase | / | 0.706 | |
1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.705 | |
1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.705 | |
1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.704 | |
3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.704 | |
1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.703 | |
3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.703 | |
4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.703 | |
5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.703 | |
1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.701 | |
4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.701 | |
1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.700 | |
3bg7 | FAD | Pyranose 2-oxidase | / | 0.700 | |
2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.699 | |
3axb | FAD | Putative oxidoreductase | / | 0.699 | |
4cnk | FAD | L-amino acid oxidase | / | 0.699 | |
2b9y | FAD | Putative aminooxidase | / | 0.697 | |
5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.697 | |
3atq | FDA | Conserved Archaeal protein | / | 0.695 | |
4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.695 | |
2b9x | FAD | Putative aminooxidase | / | 0.694 | |
4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.694 | |
3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.693 | |
4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.692 | |
4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.692 | |
2cvj | FAD | Thioredoxin reductase related protein | / | 0.690 | |
4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.690 | |
4mok | FAD | Pyranose 2-oxidase | / | 0.688 | |
4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.687 | |
3cgb | FAD | Coenzyme A disulfide reductase | / | 0.686 | |
3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.686 | |
5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.686 | |
3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.685 | |
4bjz | FAD | Probable salicylate monooxygenase | / | 0.685 | |
4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.685 | |
1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.684 | |
1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.684 | |
2bab | FAD | Putative aminooxidase | / | 0.684 | |
4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.684 | |
4opu | FDA | Conserved Archaeal protein | / | 0.684 | |
4bk2 | FAD | Probable salicylate monooxygenase | / | 0.683 | |
4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.683 | |
5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.683 | |
2ba9 | FAD | Putative aminooxidase | / | 0.682 | |
3qj4 | FAD | Renalase | / | 0.682 | |
1rsg | FAD | Polyamine oxidase FMS1 | / | 0.681 | |
2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.681 | |
4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.681 | |
4opl | FDA | Conserved Archaeal protein | / | 0.680 | |
2whd | FAD | Thioredoxin reductase | / | 0.679 | |
3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.679 | |
2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.678 | |
3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.678 | |
4opg | FDA | Conserved Archaeal protein | / | 0.678 | |
1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.677 | |
3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.677 | |
4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.677 | |
4opi | FDA | Conserved Archaeal protein | / | 0.677 | |
2e1m | FAD | L-glutamate oxidase | / | 0.676 | |
3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.676 | |
4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.676 | |
5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.675 | |
2igo | FAD | Pyranose 2-oxidase | / | 0.674 | |
4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.674 | |
2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.673 | |
2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.673 | |
3cgc | FAD | Coenzyme A disulfide reductase | / | 0.673 | |
4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.673 | |
4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.673 | |
4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.673 | |
3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.672 | |
3pl8 | FAD | Pyranose 2-oxidase | / | 0.671 | |
3r9u | FAD | Thioredoxin reductase | / | 0.671 | |
4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.671 | |
3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.670 | |
4opc | FDA | Conserved Archaeal protein | / | 0.670 | |
1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.669 | |
3vqr | FAD | Putative oxidoreductase | / | 0.669 | |
1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.668 | |
3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.668 | |
2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.667 | |
3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.667 | |
4opt | FDA | Conserved Archaeal protein | / | 0.667 | |
3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.666 | |
3nlc | FAD | Uncharacterized protein | / | 0.666 | |
1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.665 | |
1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.664 | |
2q7v | FAD | Thioredoxin reductase | / | 0.663 | |
4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.663 | |
2yg5 | FAD | Putrescine oxidase | / | 0.662 | |
3lsm | SFD | Pyranose 2-oxidase | / | 0.662 | |
1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.661 | |
4ynt | FDA | Glucose oxidase, putative | / | 0.661 | |
2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.660 | |
2ywl | FAD | Thioredoxin reductase related protein | / | 0.660 | |
3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.660 | |
4jn9 | FAD | DepH | / | 0.659 | |
2ign | FAD | Pyranose 2-oxidase | / | 0.658 | |
2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.658 | |
4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.658 | |
4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.657 | |
3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.656 | |
3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.656 | |
3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.655 | |
3rha | FDA | Putrescine oxidase | / | 0.655 | |
1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.654 | |
3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.654 | |
2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.653 | |
2yg6 | FAD | Putrescine oxidase | / | 0.653 | |
3cgd | FAD | Coenzyme A disulfide reductase | / | 0.653 | |
3cge | FAD | Coenzyme A disulfide reductase | / | 0.653 | |
3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.653 | |
1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.652 | |
4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.652 | |
4i58 | FAD | Cyclohexylamine Oxidase | / | 0.652 | |
4u8o | FDA | UDP-galactopyranose mutase | / | 0.652 | |
1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.651 | |
4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.651 | |
4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.651 | |
4u8n | FDA | UDP-galactopyranose mutase | / | 0.651 | |
1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.650 | |
2jae | FAD | L-amino acid oxidase | / | 0.650 | |
3k4n | FAD | Pyranose 2-oxidase | / | 0.650 | |
3lov | FAD | Protoporphyrinogen oxidase | / | 0.650 |