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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3pxy JWS Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3pxy JWSCyclin-dependent kinase 2 2.7.11.22 0.949
3qqg X06Cyclin-dependent kinase 2 2.7.11.22 0.818
3qzf X66Cyclin-dependent kinase 2 2.7.11.22 0.759
3ql8 X01Cyclin-dependent kinase 2 2.7.11.22 0.736
2obj VRVSerine/threonine-protein kinase pim-1 2.7.11.1 0.686
3fz1 B98Cyclin-dependent kinase 2 2.7.11.22 0.670
3qcq 3Q03-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.660
4dgo 0JWCasein kinase II subunit alpha 2.7.11.1 0.659
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.657
5bmv VLBTubulin alpha-1B chain / 0.656
5bmv VLBTubulin beta chain / 0.656