sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3p19 | NDP | Putative blue fluorescent protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3p19 | NDP | Putative blue fluorescent protein | / | 1.484 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 1.144 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 1.017 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 1.015 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.998 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.986 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.978 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.971 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.964 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.959 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.950 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.944 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.944 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.941 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.940 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.939 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.932 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.931 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.913 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.911 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.904 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.900 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.898 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.897 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.897 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.896 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.895 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.894 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.892 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.891 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.883 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.880 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.878 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.877 | |
| 4kwh | NAP | Reductase homolog | / | 0.877 | |
| 4hxy | NDP | Plm1 | / | 0.874 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.873 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.872 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.871 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.870 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.867 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.865 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.864 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.863 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.862 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.861 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.860 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.856 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.853 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.849 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.848 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.847 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.846 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.843 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.842 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.842 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.842 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.841 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.839 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.838 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.838 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.838 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.838 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.835 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.834 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.833 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.833 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.831 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.830 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.827 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.826 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.825 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.825 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.824 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.824 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.823 | |
| 5d2e | NAP | MlnE | / | 0.823 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.819 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.818 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.817 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.815 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.814 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.813 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.811 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.810 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.810 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.807 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.806 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.806 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.805 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.804 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.804 | |
| 4qec | NAP | ElxO | / | 0.804 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.803 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.803 | |
| 1sny | NAP | LD36273p | / | 0.801 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.801 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.800 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.798 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.797 | |
| 4u7w | NDP | MxaA | / | 0.794 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.792 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.791 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.791 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.788 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.788 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.787 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.787 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.786 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.785 | |
| 3uce | NDP | Dehydrogenase | / | 0.785 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.783 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.782 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.780 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.778 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.778 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.778 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.778 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.777 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.777 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.777 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.775 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.774 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.774 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.774 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.773 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.773 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.772 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.770 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.769 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.767 | |
| 3bmo | NAP | Pteridine reductase | / | 0.766 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.766 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.765 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.765 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.765 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.764 | |
| 4qed | NAP | ElxO | / | 0.764 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.762 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.762 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.761 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.760 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.759 | |
| 3sju | NDP | Keto reductase | / | 0.758 | |
| 1iy8 | NAD | Levodione reductase | / | 0.754 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.754 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.753 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.753 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.752 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.752 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.751 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.750 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.749 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.749 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.747 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.746 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.746 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.745 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.745 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.743 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.742 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.741 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.739 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.737 | |
| 4clo | NAP | Pteridine reductase | / | 0.737 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.737 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.736 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.736 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.735 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.734 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.734 | |
| 3mje | NDP | AmphB | / | 0.734 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.734 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.728 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.727 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.727 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.725 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.724 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.724 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.723 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.723 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.722 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.722 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.721 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.720 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.719 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.719 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.719 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.718 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.718 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.717 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.717 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.716 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.716 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.716 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.716 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.715 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.714 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.714 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.711 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.709 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.709 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.709 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.708 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.707 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.704 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.703 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.703 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.701 | |
| 4l4x | NDP | AmphI | / | 0.701 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.700 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.700 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.699 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.699 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.699 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.698 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.698 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.697 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.696 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.695 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.694 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.693 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.693 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.691 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.691 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.691 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.691 | |
| 1djl | NAP | NAD(P) transhydrogenase, mitochondrial | 1.6.1.2 | 0.690 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.688 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.687 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.686 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.685 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.685 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.685 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.684 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.683 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.682 | |
| 1r37 | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.681 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.681 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.680 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.679 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.679 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.679 | |
| 5aq1 | NDP | Glucose-6-phosphate 1-dehydrogenase | / | 0.679 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.678 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.678 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.677 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.677 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.676 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.674 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.672 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.672 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.671 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.671 | |
| 4j16 | NAP | NAD(P) transhydrogenase subunit beta | / | 0.670 | |
| 1i36 | NAP | Conserved protein | / | 0.668 | |
| 2yjz | NAP | Metalloreductase STEAP4 | 1.16.1 | 0.668 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.668 | |
| 1u31 | NDP | NAD(P) transhydrogenase, mitochondrial | 1.6.1.2 | 0.667 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.667 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.666 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.666 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.665 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.664 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.663 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.663 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.663 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.661 | |
| 3c1o | NAP | Eugenol synthase | / | 0.661 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.660 | |
| 2b5v | NAP | Glucose 1-dehydrogenase | / | 0.659 | |
| 1d4o | NAP | NAD(P) transhydrogenase, mitochondrial | / | 0.658 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.658 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.658 | |
| 4hmw | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.658 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.657 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.655 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.655 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.655 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.654 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.653 | |
| 3abi | NAD | Uncharacterized protein | / | 0.653 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.653 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.653 | |
| 5a02 | NAP | Glucose-fructose oxidoreductase | / | 0.653 | |
| 5a04 | NDP | Glucose-fructose oxidoreductase | / | 0.653 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.651 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.651 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.650 |