sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 1.433 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.994 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.951 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.933 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.921 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.909 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.908 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.905 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.899 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.895 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.895 | |
| 2qa1 | FAD | PgaE | / | 0.893 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.890 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.883 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.881 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.878 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.878 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.877 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.874 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.872 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.869 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.867 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.867 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.865 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.865 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.863 | |
| 2wow | FAD | Trypanothione reductase | / | 0.862 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.862 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.862 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.858 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.857 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.855 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.855 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.855 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.854 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.854 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.853 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.849 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.849 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.849 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.849 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.848 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.848 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.845 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.845 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.844 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.844 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.844 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.843 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.842 | |
| 4nev | FAD | Trypanothione reductase | / | 0.840 | |
| 4x4j | FAD | Putative oxygenase | / | 0.840 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.838 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.837 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.836 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.836 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.836 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.836 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.835 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.830 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.829 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.828 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.827 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.826 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.824 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.824 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.824 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.823 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.823 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.822 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.822 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.821 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.819 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.818 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.817 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.816 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.816 | |
| 4jn9 | FAD | DepH | / | 0.816 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.813 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.813 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.813 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.813 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.812 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.812 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.811 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.811 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.810 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.809 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.809 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.809 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.808 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.808 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.808 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.807 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.807 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.805 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.804 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.803 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.803 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.802 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.801 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.801 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.801 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.798 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.798 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.797 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.797 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.797 | |
| 4icy | FAD | PgaE | / | 0.797 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.797 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.797 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.796 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.796 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.795 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.795 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.795 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.794 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.794 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.791 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.791 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.790 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.790 | |
| 3fbs | FAD | Oxidoreductase | / | 0.790 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.789 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.787 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.787 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.786 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.785 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.784 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.783 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.783 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.783 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.783 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.782 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.781 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.780 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.779 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.779 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.778 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.776 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.776 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.775 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.774 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.774 | |
| 4nte | FAD | DepH | / | 0.773 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.772 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.772 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.771 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.771 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.770 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.770 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.769 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.769 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.768 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.768 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.768 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.768 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.767 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.765 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.765 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.765 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.765 | |
| 4tm3 | FAD | KtzI | / | 0.765 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.764 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.764 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.764 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.762 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.762 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.761 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.761 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.761 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.761 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.760 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.759 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.759 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.759 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.759 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.758 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.757 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.756 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.756 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.756 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.755 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.755 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.755 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.755 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.755 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.754 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.753 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.751 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.751 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.751 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.750 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.750 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.750 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.750 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.750 | |
| 4usr | FAD | Monooxygenase | / | 0.750 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.749 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.749 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.748 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.748 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.748 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.748 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.747 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.747 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.746 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.746 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.745 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.745 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.743 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.742 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.742 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.742 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.741 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.740 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.740 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.740 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.739 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.738 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.738 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.738 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.738 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.738 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.736 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.735 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.733 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.733 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.733 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.732 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.732 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.731 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.731 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.731 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.730 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.730 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.729 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.729 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.729 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.728 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.728 | |
| 2bab | FAD | Putative aminooxidase | / | 0.727 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.727 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.727 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.726 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.726 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.725 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.724 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.724 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.724 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.723 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.723 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.723 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.723 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.723 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.722 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.722 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.721 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.721 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.721 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.721 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.721 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.720 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.718 | |
| 2bac | FAD | Putative aminooxidase | / | 0.718 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.718 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.718 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.717 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.717 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.717 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.717 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.716 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.716 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.715 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.715 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.714 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.714 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.713 | |
| 1y56 | ATP | Uncharacterized protein | / | 0.713 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.712 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.712 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.712 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.712 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.711 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.711 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.710 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.710 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.709 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.709 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.708 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.708 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.708 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.708 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.708 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.708 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.707 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.707 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.706 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.705 | |
| 4k5r | FAD | Oxygenase | / | 0.705 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.704 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.704 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.702 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.702 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.702 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.701 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.701 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.701 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.701 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.699 | |
| 2cdu | FAD | NADH oxidase | / | 0.699 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.699 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.699 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.698 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.698 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.696 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.696 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.695 | |
| 4tlz | FAD | KtzI | / | 0.695 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.694 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.694 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.694 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.694 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.694 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.693 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.693 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.692 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.692 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.692 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.691 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.691 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.691 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.691 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.690 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.690 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.690 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.690 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.689 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.689 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.689 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.689 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.688 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.688 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.688 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.688 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.688 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.687 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.687 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.686 | |
| 3qj4 | FAD | Renalase | / | 0.686 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.686 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.685 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.685 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.685 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.684 | |
| 4ysh | FAD | Glycine oxidase | / | 0.684 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.683 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.682 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.682 | |
| 3kkj | FAD | Renalase | / | 0.682 | |
| 1pkv | RBF | Riboflavin synthase | 2.5.1.9 | 0.681 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.681 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.681 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.681 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.681 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.681 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.680 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.680 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.680 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.680 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.679 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.679 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.678 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.678 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.678 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.678 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.678 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.678 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.677 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.677 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.677 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.676 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.676 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.675 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.675 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.675 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.675 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.675 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.673 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.673 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.673 | |
| 4tm4 | FDA | KtzI | / | 0.673 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.673 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.672 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.672 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.671 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.671 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.671 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.670 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.670 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.670 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.669 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.669 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.669 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.668 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.668 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.668 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.668 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.668 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.667 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.666 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.666 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.666 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.665 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.665 | |
| 1h2h | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.664 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.664 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.662 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.662 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.661 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.661 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.661 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.660 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.659 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.659 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.659 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.659 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.659 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.658 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.658 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.658 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.657 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.655 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.655 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.654 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.654 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.654 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.653 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.653 | |
| 3fmw | FAD | Oxygenase | / | 0.653 | |
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 0.653 | |
| 4tlx | FDA | KtzI | / | 0.653 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.653 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.652 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.652 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.652 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.652 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.652 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.652 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.651 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.651 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.651 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 5epe | SAH | Uncharacterized protein | / | 0.651 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.650 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.650 |