Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ort AGS Serine/threonine protein kinase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3ort AGSSerine/threonine protein kinase / 1.001
3orp AGSSerine/threonine protein kinase / 0.988
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.786
3oro AGSSerine/threonine protein kinase / 0.764
4bfm ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.750
3ork AGSSerine/threonine protein kinase / 0.717
3igo ANPCalmodulin-domain protein kinase 1, putative / 0.716
4axd ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.715
2wqe ADPAurora kinase A 2.7.11.1 0.712
4ct2 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.708
4yhj AN2G protein-coupled receptor kinase 4 2.7.11.16 0.706
1q8y ADPSerine/threonine-protein kinase SKY1 2.7.11.1 0.701
3nsz ANPCasein kinase II subunit alpha 2.7.11.1 0.701
3ori AGSSerine/threonine protein kinase / 0.701
4fl2 ANPTyrosine-protein kinase SYK 2.7.10.2 0.700
4jqe ANPCasein kinase II subunit alpha 2.7.11.1 0.700
4qml ANPSerine/threonine-protein kinase 24 2.7.11.1 0.700
3gu4 ANPDeath-associated protein kinase 1 2.7.11.1 0.699
3nie ANPMitogen-activated protein kinase / 0.697
1cdk ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.695
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.695
4h3q ANPMitogen-activated protein kinase 1 2.7.11.24 0.695
3orm AGSSerine/threonine protein kinase / 0.693
3llt ANPProtein serine/threonine kinase-1 / 0.687
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.683
4lv7 ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.683
4wb6 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.682
1mru AGSSerine/threonine-protein kinase PknB 2.7.11.1 0.679
1q99 ANPSerine/threonine-protein kinase SKY1 2.7.11.1 0.678
4ysj ADPCalmodulin-like domain protein kinase / 0.678
4ib3 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.677
5cvh ADPCasein kinase II subunit alpha 2.7.11.1 0.677
1hck ATPCyclin-dependent kinase 2 2.7.11.22 0.676
2y9q ANPMitogen-activated protein kinase 1 2.7.11.24 0.676
4nif ANPMitogen-activated protein kinase 1 2.7.11.24 0.676
4xw6 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.674
4aqk ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.673
1lp4 ANPCasein kinase II subunit alpha 2.7.11.1 0.672
2xan ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.671
4jrn ANPRhoptry kinase family protein / 0.671
4c3r ACPAurora kinase A 2.7.11.1 0.668
3a8w ATPProtein kinase C iota type 2.7.11.13 0.667
4axf ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.667
2gs7 ANPEpidermal growth factor receptor 2.7.10.1 0.666
2qcs ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
3fhi ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
4fl3 ANPTyrosine-protein kinase SYK 2.7.10.2 0.666
3hko ANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands / 0.664
4qpm ADPMitotic checkpoint serine/threonine-protein kinase BUB1 2.7.11.1 0.664
3fjq ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.662
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.662
3bu5 ATPInsulin receptor 2.7.10.1 0.661
5e92 ANPTGF-beta receptor type-2 2.7.11.30 0.661
2hen ADPEphrin type-B receptor 2 2.7.10.1 0.660
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.660
2pul ACPMethylthioribose kinase 2.7.1.100 0.659
4rrv ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.659
1zth ADPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.658
2cci ATPCyclin-dependent kinase 2 2.7.11.22 0.657
5dmz ADPMitotic checkpoint serine/threonine-protein kinase BUB1 2.7.11.1 0.657
4r8q ADPMitotic checkpoint serine/threonine-protein kinase BUB1 2.7.11.1 0.656
1b38 ATPCyclin-dependent kinase 2 2.7.11.22 0.655
3gu5 ANPDeath-associated protein kinase 1 2.7.11.1 0.655
4xlv ACPInsulin receptor 2.7.10.1 0.655
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.654
1o6y ACPSerine/threonine-protein kinase PknB 2.7.11.1 0.653
5cnn ANPEpidermal growth factor receptor 2.7.10.1 0.653
5cvf ATPCasein kinase II subunit alpha 2.7.11.1 0.653
4ceg ADPAurora kinase A 2.7.11.1 0.652
4ock ANPN-acetylhexosamine 1-kinase 2.7.1.162 0.652
2qoq ANPEphrin type-A receptor 3 2.7.10.1 0.651
3gu7 ADPDeath-associated protein kinase 1 2.7.11.1 0.651
4nm5 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.651
4otp ADPSerine/threonine-protein kinase RIO1 2.7.11.1 0.651
2pyw ADPMethylthioribose kinase 2.7.1.100 0.650
4ej7 ATPAminoglycoside 3'-phosphotransferase AphA1-IAB / 0.650