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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3o8t BMU Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3o8t BMUMitogen-activated protein kinase 14 / 1.042
1kv1 BMUMitogen-activated protein kinase 14 / 0.879
3p79 P79Mitogen-activated protein kinase 14 / 0.842
3o8u BMUMitogen-activated protein kinase 14 / 0.836
3oc1 BMUMitogen-activated protein kinase 14 / 0.827
3p78 P78Mitogen-activated protein kinase 14 / 0.817
1w82 L10Mitogen-activated protein kinase 14 / 0.800
3gcs BAXMitogen-activated protein kinase 14 / 0.792
3o8p BMUMitogen-activated protein kinase 14 / 0.782
3hv3 R49Mitogen-activated protein kinase 14 / 0.781
3p7c P7CMitogen-activated protein kinase 14 / 0.768
4e5i 0N9Polymerase acidic protein / 0.744
3p7b P7BMitogen-activated protein kinase 14 / 0.737
3p5k P5KMitogen-activated protein kinase 14 / 0.729
1wbn L09Mitogen-activated protein kinase 14 / 0.720
3nnx EDDMitogen-activated protein kinase 14 / 0.715
3npc B96Mitogen-activated protein kinase 9 2.7.11.24 0.713
3hv7 1AUMitogen-activated protein kinase 14 / 0.712
2yis YISMitogen-activated protein kinase 14 / 0.704
2yiw YIWMitogen-activated protein kinase 14 / 0.704
4f7j 0SUCyclin-dependent kinase 8 2.7.11.22 0.703
4k9y K9YFocal adhesion kinase 1 2.7.10.2 0.703
3uvr 06FMitogen-activated protein kinase 14 / 0.697
4f7n 0SVCyclin-dependent kinase 8 2.7.11.22 0.685
3nnw EDDMitogen-activated protein kinase 14 / 0.683
1w83 L11Mitogen-activated protein kinase 14 / 0.681
4f70 0STCyclin-dependent kinase 8 2.7.11.22 0.679
3hv4 L51Mitogen-activated protein kinase 14 / 0.678
4eyj N61Mitogen-activated protein kinase 13 2.7.11.24 0.678
3bv2 P38Mitogen-activated protein kinase 14 / 0.677
4neu Q1AReceptor-interacting serine/threonine-protein kinase 1 2.7.11.1 0.673
1wbv LI3Mitogen-activated protein kinase 14 / 0.672
3wze BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.668
4f6s 0SQCyclin-dependent kinase 8 2.7.11.22 0.668
3lfb Z87Mitogen-activated protein kinase 14 / 0.663
3lfe Z84Mitogen-activated protein kinase 14 / 0.663
3uxv GUNNADPH-dependent 7-cyano-7-deazaguanine reductase / 0.657
4f6w 0SSCyclin-dependent kinase 8 2.7.11.22 0.655
5hid B1ESerine/threonine-protein kinase B-raf 2.7.11.1 0.654
2puu G2GMitogen-activated protein kinase 14 / 0.652
4aa0 AA0Mitogen-activated protein kinase 14 / 0.651
5hi2 BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.651