Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ln3 NAD Aldo-keto reductase family 1 member C13

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3ln3 NADAldo-keto reductase family 1 member C13 / 1.391
2hdj NDPAldo-keto reductase family 1 member C2 / 0.919
4xo7 NAPAldo-keto reductase family 1 member C2 / 0.912
4jtq NAPAldo-keto reductase family 1 member C2 / 0.877
4jq3 NAPAldo-keto reductase family 1 member C2 / 0.876
3h7r NAPAldo-keto reductase family 4 member C8 / 0.873
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.857
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 0.851
4l1x NAPAldo-keto reductase family 1 member C2 / 0.834
1s1p NAPAldo-keto reductase family 1 member C3 / 0.827
2acs NAPAldose reductase 1.1.1.21 0.823
2hej NDPAldo-keto reductase family 1 member C21 1.1.1 0.816
2p5n NDPAldo-keto reductase family 1 member C21 1.1.1 0.813
4g5d NDPProstaglandin F synthase 1.1.1.188 0.813
1ef3 NAPAldose reductase 1.1.1.21 0.809
2iq0 NAPAldose reductase 1.1.1.21 0.807
2pev NDPAldose reductase 1.1.1.21 0.805
2acu NAPAldose reductase 1.1.1.21 0.804
3qkz NAPAldose reductase-related protein 1 1.1.1.21 0.801
4dz5 NAPAldo-keto reductase family 1 member C3 / 0.799
1s1r NAPAldo-keto reductase family 1 member C3 / 0.798
1x96 NAPAldose reductase 1.1.1.21 0.797
3wcz NAPAldo-keto reductase AKR2E4 / 0.797
2acq NAPAldose reductase 1.1.1.21 0.795
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.791
2pf8 NDPAldose reductase 1.1.1.21 0.791
1x98 NAPAldose reductase 1.1.1.21 0.790
1z8a NAPAldose reductase 1.1.1.21 0.787
2bgs NDPAldose reductase 1.1.1.21 0.787
2j8t NAPAldose reductase 1.1.1.21 0.783
2vdg NDPAldose reductase 1.1.1.21 0.781
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.778
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.772
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.765
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.765
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.765
3q67 NAPAldose reductase 1.1.1.21 0.764
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.760
2pfh NDPAldose reductase 1.1.1.21 0.754
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.751
1vp5 NAPOxidoreductase, aldo/keto reductase family / 0.751
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.751
1ads NAPAldose reductase 1.1.1.21 0.747
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.743
3v36 NAPAldose reductase 1.1.1.21 0.742
4xzn NAPAldo-keto reductase family 1 member B10 1.1.1 0.740
1a80 NDP2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.738
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.736
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.736
1og6 NAPOxidoreductase YdhF 1 0.733
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.732
4pmj NAPPutative oxidoreductase / 0.731
2clp NDPAflatoxin B1 aldehyde reductase member 3 / 0.728
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.722
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.721
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.720
1az2 NAPAldose reductase 1.1.1.21 0.715
5c7h NDPPutative oxidoreductase / 0.714
3o3r NAPAldose reductase-related protein 1 1.1.1.21 0.710
3wbw NDPPutative 2,5-diketo-D-gluconic acid reductase / 0.709
2he5 NDPAldo-keto reductase family 1 member C21 1.1.1 0.707
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.707
4jta NAPVoltage-gated potassium channel subunit beta-2 / 0.706
1m9h NAD2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.699
1pz1 NAPGeneral stress protein 69 / 0.685
1pz0 NAPProtein IolS 1.1.1 0.683
1hqt NAPAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.681
3q65 NAPAldose reductase 1.1.1.21 0.681
1ah4 NAPAldose reductase 1.1.1.21 0.677
1zgd NAPChalcone reductase / 0.677
3wg6 NDPNADPH-dependent conjugated polyketone reductase C1 / 0.671
2bp1 NDPAflatoxin B1 aldehyde reductase member 2 / 0.666
2r9r NAPVoltage-gated potassium channel subunit beta-2 / 0.660
2p0a ANPSynapsin-3 / 0.656
4h8n NDPNADPH-dependent conjugated polyketone reductase C2 / 0.652
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.650