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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3l9n L9N cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3l9n L9NcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 1.128
3l9m L9McAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.944
3l9l L9LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.810
2jds L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.786
3vqh IQBcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.717
2uzw SS4cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.711
2hxl 422Serine/threonine-protein kinase Chk1 2.7.11.1 0.709
2uzu L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.704
1pmv 537Mitogen-activated protein kinase 10 2.7.11.24 0.701
2oh0 2PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.701
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.695
4agu D15Cyclin-dependent kinase-like 1 / 0.693
2jdv L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.692
2f7e 2EAcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.691
2uzv SS5cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.684
1ydr IQPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.683
3qcs 3Q13-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.677
2zv2 609Calcium/calmodulin-dependent protein kinase kinase 2 2.7.11.17 0.675
3py0 SU9Cyclin-dependent kinase 2 2.7.11.22 0.668
2ojf 4PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
2hy0 306Serine/threonine-protein kinase Chk1 2.7.11.1 0.665
2uzt SS3cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
3hzt J60Calmodulin-like domain protein kinase isoform 3 / 0.661
3cxw 7CPSerine/threonine-protein kinase pim-1 2.7.11.1 0.658
4qmw KS1Serine/threonine-protein kinase 24 2.7.11.1 0.658
2gdo 12CSerine/threonine-protein kinase Chk1 2.7.11.1 0.657
3mvj XFEcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.657
1exv 700Glycogen phosphorylase, liver form 2.4.1.1 0.654
3mv5 XFERAC-alpha serine/threonine-protein kinase 2.7.11.1 0.654
2gni M77cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.653
4c59 FEFCyclin-G-associated kinase 2.7.11.1 0.653
4kfg DOODNA gyrase subunit B / 0.652
1rek B8LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
1uv5 BRWGlycogen synthase kinase-3 beta 2.7.11.26 0.651
3qrt X14Cyclin-dependent kinase 2 2.7.11.22 0.650
4fsu HK5Serine/threonine-protein kinase Chk1 2.7.11.1 0.650