sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ket | NAD | Redox-sensing transcriptional repressor Rex |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3ket | NAD | Redox-sensing transcriptional repressor Rex | / | 0.940 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.825 | |
| 3keo | NAD | Redox-sensing transcriptional repressor Rex | / | 0.797 | |
| 3adp | NAI | Lambda-crystallin | 1.1.1.45 | 0.767 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.734 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.722 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.710 | |
| 3q2k | NAI | Probable oxidoreductase | / | 0.710 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.706 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.706 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.704 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.694 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.693 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.692 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.690 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.689 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.685 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.681 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.679 | |
| 1m76 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.679 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.679 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.678 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.678 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.678 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.677 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.675 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.675 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.675 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.674 | |
| 4om8 | NAD | 3-hydroxybutyryl-coA dehydrogenase | / | 0.672 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.671 | |
| 2ixa | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.669 | |
| 3b1j | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.669 | |
| 2ixb | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.668 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.668 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.667 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.667 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.666 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.665 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.664 | |
| 3m2t | NAD | Probable dehydrogenase | / | 0.664 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.663 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.663 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.662 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.661 | |
| 1r37 | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.659 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.658 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.657 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.657 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.656 | |
| 3ntq | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.656 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.656 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.655 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.655 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.652 | |
| 5a04 | NDP | Glucose-fructose oxidoreductase | / | 0.652 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.651 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.651 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.651 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.651 |