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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gyt DL4 Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3gyt DL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 1.369
3gyu DL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.972
3up0 D7SaceDAF-12 / 0.971
3gki CLRNiemann-Pick C1 protein / 0.716
2hrc CHDFerrochelatase, mitochondrial 4.99.1.1 0.680
2qd4 CHDFerrochelatase, mitochondrial 4.99.1.1 0.673
1kdm DHTSex hormone-binding globulin / 0.672
2aib ERGBeta-elicitin cinnamomin / 0.670
3kyt HC2Nuclear receptor ROR-gamma / 0.666
3up3 XCAaceDAF-12 / 0.661
4a81 DXCMajor pollen allergen Bet v 1-A / 0.651