Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3fl9 TOP Dihydrofolate reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3fl9 TOPDihydrofolate reductase / 0.971
3fre TOPDihydrofolate reductase 1.5.1.3 0.722
4elg 52JDihydrofolate reductase / 0.716
3jw3 TOPDihydrofolate reductase / 0.714
4elb 34SDihydrofolate reductase / 0.713
4g8z TOPDihydrofolate reductase 1.5.1.3 0.652