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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3f82 353 Hepatocyte growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3f82 353Hepatocyte growth factor receptor 2.7.10.1 1.351
3ctj 320Hepatocyte growth factor receptor 2.7.10.1 0.872
3cth 319Hepatocyte growth factor receptor 2.7.10.1 0.854
3vw8 DF6Hepatocyte growth factor receptor 2.7.10.1 0.822
3ce3 1FNHepatocyte growth factor receptor 2.7.10.1 0.727
4eev L1XHepatocyte growth factor receptor 2.7.10.1 0.709
3k3j F4CMitogen-activated protein kinase 14 / 0.661
3hv3 R49Mitogen-activated protein kinase 14 / 0.651