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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3efl 706 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3efl 706Vascular endothelial growth factor receptor 2 2.7.10.1 1.192
2p2i 608Vascular endothelial growth factor receptor 2 2.7.10.1 0.924
3hng 8STVascular endothelial growth factor receptor 1 2.7.10.1 0.810
3cp9 C19Vascular endothelial growth factor receptor 2 2.7.10.1 0.719
3vhk BPKVascular endothelial growth factor receptor 2 2.7.10.1 0.692
2qu6 857Vascular endothelial growth factor receptor 2 2.7.10.1 0.690
4ag8 AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.686
4agc AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.669
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.668
4uxq 0LIFibroblast growth factor receptor 4 2.7.10.1 0.664
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.662
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.660
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.659
4kiq 1RAMitogen-activated protein kinase 14 / 0.653