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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3dyn PCG High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3dyn PCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.872
3dyl PCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.796
3dy8 5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.782
3dys 5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.772
3dyq PCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.732
5iqf GDPBifunctional AAC/APH 2.3.1 0.695
5iqi GNPBifunctional AAC/APH 2.3.1 0.684
5iqb GNPBifunctional AAC/APH 2.3.1 0.672
5iqh GNPBifunctional AAC/APH 2.3.1 0.669
5iqa GNPBifunctional AAC/APH 2.3.1 0.667
5iqd GNPBifunctional AAC/APH 2.3.1 0.664
5iqg GDPBifunctional AAC/APH 2.3.1 0.660
3ufx GDPSuccinate--CoA ligase [GDP-forming] subunit beta / 0.654
3gfz C2EUncharacterized protein / 0.653