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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3dtw A96 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3dtw A96Vascular endothelial growth factor receptor 2 2.7.10.1 1.131
4u0i 0LIMast/stem cell growth factor receptor Kit 2.7.10.1 0.819
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.771
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.768
4tyj 0LIFibroblast growth factor receptor 4 2.7.10.1 0.743
2hiw 7MPTyrosine-protein kinase ABL1 2.7.10.2 0.715
4equ G6ISerine/threonine-protein kinase 10 2.7.11.1 0.710
4ckr DI1Epithelial discoidin domain-containing receptor 1 2.7.10.1 0.695
4qrc 0LIFibroblast growth factor receptor 4 2.7.10.1 0.691
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.690
4uxq 0LIFibroblast growth factor receptor 4 2.7.10.1 0.690
2e2b 406Tyrosine-protein kinase ABL1 2.7.10.2 0.682
2og8 1N8Tyrosine-protein kinase Lck 2.7.10.2 0.681
2p4i MR9Angiopoietin-1 receptor 2.7.10.1 0.674
3b2w 9NHTyrosine-protein kinase Lck 2.7.10.2 0.671
3p7c P7CMitogen-activated protein kinase 14 / 0.671
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.668