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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3d91 REM Renin 3.4.23.15

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3d91 REMRenin 3.4.23.15 1.417
1rne C60Renin 3.4.23.15 0.886
2jji 0QSEndothiapepsin 3.4.23.22 0.756
1psa 0ZLPepsin A 3.4.23.1 0.751
1e81 M91Endothiapepsin 3.4.23.22 0.750
1od1 0QSEndothiapepsin 3.4.23.22 0.743
2g20 L1ARenin 3.4.23.15 0.743
1e80 0GQEndothiapepsin 3.4.23.22 0.740
2jjj 0QSEndothiapepsin 3.4.23.22 0.718
1e82 M90Endothiapepsin 3.4.23.22 0.715
1qrp HH0Pepsin A-4 3.4.23.1 0.692
1gvt 2ZSEndothiapepsin 3.4.23.22 0.690
1ppk IVVPenicillopepsin-1 3.4.23.20 0.675
1bxo PP7Penicillopepsin-1 3.4.23.20 0.659
3own 3OWRenin 3.4.23.15 0.659
1ppm 0P1Penicillopepsin-1 3.4.23.20 0.655
1xe5 5FEPlasmepsin-2 3.4.23.39 0.654
2g94 ZPQBeta-secretase 1 3.4.23.46 0.653
1bxq PP8Penicillopepsin-1 3.4.23.20 0.652
3veu 0GOBeta-secretase 1 3.4.23.46 0.651
2f3e AXQBeta-secretase 1 3.4.23.46 0.650