Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3d8b ADP Fidgetin-like protein 1 3.6.4

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3d8b ADPFidgetin-like protein 1 3.6.4 0.996
3hu1 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.879
4ko8 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.819
1in5 ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.815
4kln AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.793
1um8 ADPATP-dependent Clp protease ATP-binding subunit ClpX / 0.789
3cf0 ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.788
3hu2 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.788
3hu3 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.785
2cea ADPATP-dependent zinc metalloprotease FtsH / 0.778
4d81 ADPAAA ATPase, central domain protein / 0.778
1njf ADPDNA polymerase III subunit tau 2.7.7.7 0.777
5irn ADPNucleotide binding oligomerization domain containing 2 / 0.769
3t1t GDPProbable gliding protein mglA / 0.766
3k1j ADPATP-dependent protease Lon / 0.762
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.761
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.761
4qos ADPPsp operon transcriptional activator / 0.759
4hse ADPChaperone protein ClpB / 0.755
2qen ADPWalker-Type ATPase / 0.754
1xnj ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.7.1.25 0.753
2y65 ADPKinesin heavy chain / 0.753
3cph GDPRas-related protein SEC4 / 0.753
4kod ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.753
1gia GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.752
1z0f GDPRas-related protein Rab-14 / 0.752
1e1q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.751
2c96 ATPPsp operon transcriptional activator / 0.751
2pg2 ADPKinesin-like protein KIF11 / 0.751
2zfi ADPKinesin-like protein KIF1A / 0.751
1xmv ADPProtein RecA / 0.750
2ce7 ADPATP-dependent zinc metalloprotease FtsH / 0.750
2gks ADPProbable bifunctional SAT/APS kinase 2.7.1.25 0.750
1w0k ADPATP synthase subunit alpha, mitochondrial / 0.749
1w0k ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.749
3tif ADPUncharacterized ABC transporter ATP-binding protein MJ0796 / 0.749
4pao GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.749
1ofh ADPATP-dependent protease ATPase subunit HslU / 0.748
3cx6 GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.748
2jiz ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.747
1ow3 GDPTransforming protein RhoA / 0.745
4l8g GDPGTPase KRas / 0.745
4obe GDPGTPase KRas / 0.745
1mma ADPMyosin-2 heavy chain / 0.744
4gp6 ADPMetallophosphoesterase / 0.744
4lrw GDPGTPase KRas / 0.744
4luc GDPGTPase KRas / 0.744
3l1c ADPProtein claret segregational / 0.743
3r9i ADPSeptum site-determining protein MinD / 0.743
2j5x GSPADP-ribosylation factor 6 / 0.742
4lhv GDPRas-related protein Rab-8A / 0.742
1gwn GTPRho-related GTP-binding protein RhoE / 0.741
1zd9 GDPADP-ribosylation factor-like protein 8A / 0.741
2dr3 ADPUPF0273 protein PH0284 / 0.741
3l9h ADPKinesin-like protein KIF11 / 0.741
1bof GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.740
1fnn ADPORC1-type DNA replication protein / 0.740
2zro ADPProtein RecA / 0.740
3pfi ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.740
4ldj GDPGTPase KRas / 0.740
4tl8 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.740
1x1r GDPRas-related protein M-Ras / 0.739
2uyi ADPKinesin-like protein KIF11 / 0.739
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.739
2xae ADPKinesin-like protein KIF11 / 0.738
4tld AGSCircadian clock protein kinase KaiC 2.7.11.1 0.738
1gil GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.737
4bzq ADPBifunctional enzyme CysN/CysC 2.7.1.25 0.737
4lpk GDPGTPase KRas / 0.737
3cx8 GSPGuanine nucleotide-binding protein subunit alpha-13 / 0.736
2fna ADPUncharacterized protein / 0.735
2x2r ADPKinesin-like protein KIF11 / 0.735
4oi4 ATPmRNA cleavage and polyadenylation factor CLP1 / 0.735
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.734
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.734
2v7q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.734
1sdm ADPKinesin heavy chain-like protein / 0.733
1g16 GDPRas-related protein SEC4 / 0.731
3ea5 GDPGTP-binding nuclear protein Ran / 0.731
3kz1 GSPTransforming protein RhoA / 0.731
4q02 GDPGTPase KRas / 0.730
3tlx ADPAdenylate kinase 2 / 0.728
5fl3 ADPPili retraction protein PilT / 0.728
1e79 ATPATP synthase subunit alpha, mitochondrial / 0.727
1e79 ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.727
1z0a GDPRas-related protein Rab-2A / 0.727
1zio AP5Adenylate kinase / 0.727
4idn GNPAtlastin-1 3.6.5 0.727
4pjk ADPMyosin-2 heavy chain / 0.727
3kud GDPGTPase HRas / 0.725
2ax4 ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 2.7.1.25 0.724
2ql6 ADPNicotinamide riboside kinase 1 / 0.724
4o2r GDPGTP-binding protein Rheb / 0.724
1gp2 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.723
1w5t ANPORC1-type DNA replication protein 2 / 0.723
1yra GDPGPN-loop GTPase PAB0955 / 0.723
3m0e ATPTranscriptional regulator (NtrC family) / 0.723
5cyo GDPSeptin-9 / 0.723
4qbh AP5Adenylate kinase / 0.722
4ww4 ADPRuvB-like helicase / 0.720
3oee ANPATP synthase subunit alpha, mitochondrial / 0.719
3oee ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.719
4r43 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.719
1got GDPGuanine nucleotide-binding protein G(t) subunit alpha-1 / 0.717
1wbb ADPDNA mismatch repair protein MutS / 0.717
4b7b ADPKinesin-like protein KIF11 / 0.717
1ytm ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.716
3cob ADPKinesin heavy chain-like protein / 0.716
1bmf ADPATP synthase subunit alpha, mitochondrial / 0.715
1bmf ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.715
4d0l GSPRas-related protein Rab-11A / 0.715
4dzz ADPPlasmid partitioning protein ParF / 0.715
4ww0 ADPATP-dependent zinc metalloprotease FtsH / 0.715
1mmg AGSMyosin-2 heavy chain / 0.714
1sq5 ADPPantothenate kinase 2.7.1.33 0.714
2r9v ATPATP synthase subunit alpha / 0.714
1e4v AP5Adenylate kinase / 0.713
4mkh AP5Adenylate kinase / 0.713
4pfp ADPUnconventional myosin-VI / 0.713
4q03 GDPGTPase KRas / 0.713
4xvq GNPGTPase HRas / 0.713
1ht2 ADPATP-dependent protease ATPase subunit HslU / 0.712
1os1 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.712
3vhx GTPADP-ribosylation factor 6 / 0.712
4a51 ADPKinesin-like protein KIF11 / 0.712
4jlo ADPAdenylate kinase / 0.712
3onw GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.711
2x7e ADPKinesin-like protein KIF11 / 0.710
1yrs ADPKinesin-like protein KIF11 / 0.709
2dpx GDPGTP-binding protein RAD / 0.709
1p3d ANPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.708
4mkf AP5Adenylate kinase / 0.708
4tyq AP5Adenylate kinase / 0.708
3ieu GDPGTPase Era / 0.707
4kvg GTPRas-related protein Rap-1A / 0.707
1azt GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.706
1s3s ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.706
4xsg GSPTransforming protein RhoA / 0.706
1p3j AP5Adenylate kinase / 0.705
4idp GNPAtlastin-1 3.6.5 0.705
4nh0 ATPESX secretion system protein EccC / 0.705
1im2 ADPATP-dependent protease ATPase subunit HslU / 0.703
1zcb GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.703
2hld ANPATP synthase subunit alpha, mitochondrial / 0.703
2hld ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.703
4jsy GTPMetallophosphoesterase / 0.703
1e96 GTPRas-related C3 botulinum toxin substrate 1 / 0.702
1u0h GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.702
4g01 GDPRas-related protein RABF2b / 0.702
1m7b GTPRho-related GTP-binding protein RhoE / 0.701
4cvm ANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.701
4dvg GSPRho family GTPase / 0.701
1t91 GTPRas-related protein Rab-7a / 0.700
2v7q ATPATP synthase subunit alpha, mitochondrial / 0.700
2v7q ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.700
3kji ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.700
4hi0 GDPUrease accessory protein UreG / 0.700
4jl6 ADPAdenylate kinase / 0.700
5c46 GSPRas-related protein Rab-11A / 0.700
1z0d GDPRas-related protein Rab-5C / 0.699
3b1x GNPFerrous iron transport protein B / 0.699
4ap0 ADPKinesin-like protein KIF11 / 0.699
4xvr GNPGTPase HRas / 0.699
3bos CDPRegulatory inactivation of DnaA Hda protein / 0.698
3w3z GTPGTP-binding nuclear protein Ran / 0.698
2c9o ADPRuvB-like 1 3.6.4.12 0.697
2fl2 ADPKinesin-like protein KIF11 / 0.697
4ql3 GDPGTPase KRas / 0.697
1bmf ANPATP synthase subunit alpha, mitochondrial / 0.696
1bmf ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.696
1z2c GNPRho-related GTP-binding protein RhoC / 0.696
4iok ADPFormate--tetrahydrofolate ligase / 0.696
4pjj ADPUnconventional myosin-VI / 0.696
1sxj AGSReplication factor C subunit 1 / 0.695
2bku GTPGTP-binding nuclear protein Ran / 0.695
3ref GDPRho family GTPase / 0.695
2o8b ADPDNA mismatch repair protein Msh2 / 0.694
2py7 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.694
3ews ADPATP-dependent RNA helicase DDX19B 3.6.4.13 0.694
4a28 ADPKinesin-like protein KIF11 / 0.694
4ihq ADPConserved Archaeal protein / 0.694
4yqf GDPSeptin-9 / 0.694
2gvd GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.693
5aun ADPIron-sulfur cluster carrier protein / 0.693
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.692
2cl6 CAGGTPase HRas / 0.692
4c2u ANPDNA helicase / 0.692
4epw GDPGTPase KRas / 0.692
4l9s GDPGTPase HRas / 0.692
4y0v GDPADP-ribosylation factor 1, putative / 0.692
4ylg GDPADP-ribosylation factor 1, putative / 0.692
4pan GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.691
1a2b GSPTransforming protein RhoA / 0.690
4epx GDPGTPase KRas / 0.690
2zrj AGSProtein RecA / 0.689
1ank ANPAdenylate kinase / 0.688
1h8h ADPATP synthase subunit alpha, mitochondrial / 0.688
1h8h ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.688
4wa7 GDPGTPase KRas / 0.688
1w1w AGSStructural maintenance of chromosomes protein 1 / 0.687
1lfd GNPGTPase HRas / 0.686
3a4l ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.686
3pcr GTPADP-ribosylation factor 6 / 0.686
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.686
3zvm ADPBifunctional polynucleotide phosphatase/kinase 2.7.1.78 0.686
4cvl ACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.686
5bn4 ANPV-type ATP synthase alpha chain / 0.686
2ce2 GDPGTPase HRas / 0.685
2g0n GDPRas-related C3 botulinum toxin substrate 3 / 0.685
3c15 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.685
4js0 GNPCell division control protein 42 homolog / 0.685
5i67 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.685
1e32 ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.684
1v8k ANPKinesin-like protein KIF2C / 0.684
3qbt GNPRas-related protein Rab-8A / 0.684
1h65 GDPTranslocase of chloroplast 34 3.6.5 0.683
4dsu GDPGTPase KRas / 0.683
1njf AGSDNA polymerase III subunit tau 2.7.7.7 0.682
3a6p GTPGTP-binding nuclear protein Ran / 0.682
3tgp GNPGTPase HRas / 0.682
4o2l GTPGTP-binding protein Rheb / 0.682
2ic5 GNPRas-related C3 botulinum toxin substrate 3 / 0.681
3eg5 GNPCell division control protein 42 homolog / 0.681
3nbx ADPATPase RavA 3.6.3 0.681
1ayl ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.680
1b7t ADPMyosin heavy chain, striated muscle / 0.680
1r0z ATPCystic fibrosis transmembrane conductance regulator / 0.680
3k9l GNPGTPase HRas / 0.680
3x1w GDPRas-related protein Rap-1b / 0.680
2bc9 GNPGuanylate-binding protein 1 / 0.679
2w2v GTPRas-related C3 botulinum toxin substrate 2 / 0.679
4jl5 ADPAdenylate kinase / 0.679
2ffq GSPRas-related protein Rab-6B / 0.678
3kkq GDPRas-related protein M-Ras / 0.678
4a1z ADPKinesin-like protein KIF11 / 0.678
4cf7 ADPAdenylate kinase / 0.678
4tl7 ATPCircadian clock protein kinase KaiC 2.7.11.1 0.678
1p9w ANPType II secretion system protein E / 0.677
2p2l GDPRas-related C3 botulinum toxin substrate 1 / 0.677
3c16 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.677
4g5q GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.677
4wpu GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.677
3oiv GNPGTPase HRas / 0.676
1s1c GNPTransforming protein RhoA / 0.675
3qbv GDPCell division control protein 42 homolog / 0.675
4o25 GTPGTP-binding protein Rheb / 0.675
1rrg GDPADP-ribosylation factor 1 / 0.674
1xkv ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.674
4lhw GNPRas-related protein Rab-8A / 0.674
1cul GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.673
1d5c GDPGTPase (Rab6) / 0.673
1zc3 GNPRas-related protein Ral-A / 0.673
2fgj ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.673
2j7p GNPSignal recognition particle protein / 0.673
2j7p GNPSignal recognition particle receptor FtsY / 0.673
3vx4 ATPPutative ABC transporter, ATP-binding protein ComA / 0.673
4gzl GNPRas-related C3 botulinum toxin substrate 1 / 0.673
4lv6 GDPGTPase KRas / 0.673
1xef ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.672
4cym GCPRas-related protein Rab-32 / 0.672
1cxz GSPTransforming protein RhoA / 0.671
1ii6 ADPKinesin-like protein KIF11 / 0.671
1oix GDPRas-related protein Rab-11A / 0.671
1svl ADPLarge T antigen 3.6.4 0.671
1zbd GTPRas-related protein Rab-3A / 0.671
4i1v ADPDephospho-CoA kinase / 0.671
1k6m AGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 2.7.1.105 0.670
1zc4 GNPRas-related protein Ral-A / 0.670
4jky ADPAdenylate kinase / 0.670
4tq9 GDPGTPase KRas / 0.670
1uad GNPRas-related protein Ral-A / 0.669
4qnr ATPPsp operon transcriptional activator / 0.669
2olq ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.668
2rgg GNPGTPase HRas / 0.668
3k3b ADPKinesin-like protein KIF11 / 0.668
4iei ADPGene 2 protein / 0.668
1khb GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.667
3pit GNPRas-related protein M-Ras / 0.667
2jj2 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.666
3kuc GDPRas-related protein Rap-1A / 0.666
1fmw ATPMyosin-2 heavy chain / 0.664
2gil GTPRas-related protein Rab-6A / 0.664
2jlr ANPGenome polyprotein 3.4.21.91 0.664
2xto GDPGTPase IMAP family member 2 / 0.664
3ddc GNPGTPase HRas / 0.664
1ny5 ADPTranscriptional regulator (NtrC family) / 0.663
1yu9 GNPRas-related protein Rab-4A / 0.663
4qm6 GTPMetallophosphoesterase / 0.663
4v02 ATPSite-determining protein / 0.663
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.662
1z2a GDPRas-related protein Rab-23 / 0.662
2ic5 GDPRas-related C3 botulinum toxin substrate 3 / 0.662
2jiz ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.662
4l16 ADPFidgetin-like protein 1 3.6.4 0.662
1f5n GNPGuanylate-binding protein 1 / 0.661
1g17 GNPRas-related protein SEC4 / 0.661
1m2o GNPSmall COPII coat GTPase SAR1 3.6.5 0.661
2zs9 ADPPantothenate kinase 2.7.1.33 0.661
1ohh ANPATP synthase subunit alpha, mitochondrial / 0.660
1ohh ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.660
4c30 ANPDNA helicase / 0.660
4mit GTPRho-related protein racC / 0.660
2dft ADPShikimate kinase 2.7.1.71 0.659
2rge GNPGTPase HRas / 0.659
3q9l ATPSeptum site-determining protein MinD / 0.659
3zia ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.658
4hdq GNPRas-related protein Rap-1b / 0.658
4tle AGSCircadian clock protein kinase KaiC 2.7.11.1 0.658
3fkq ATPNtrC-like two-domain protein / 0.657
1i4l GDPRas-related C3 botulinum toxin substrate 1 / 0.656
3ftq GNPSeptin-2 / 0.656
4ag5 ADPType IV secretory pathway VirB4 components-like protein / 0.656
4gzm GSPRas-related C3 botulinum toxin substrate 1 / 0.656
4tl9 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.656
5c3c ADPCbbQ/NirQ/NorQ domain protein / 0.656
2c9c ATPPsp operon transcriptional activator / 0.655
2j0v GDPRac-like GTP-binding protein ARAC7 / 0.655
4jld ADPAdenylate kinase / 0.654
3jvv ACPTwitching mobility protein / 0.653
4yaf 2AMNADPH--cytochrome P450 reductase / 0.653
1e79 ADPATP synthase subunit alpha, mitochondrial / 0.652
1e79 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.652
1xd9 ADPNitrogenase iron protein 1 1.18.6.1 0.652
4ncl GDPEukaryotic translation initiation factor 5B / 0.652
4wou GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.652
3tjz GNPADP-ribosylation factor 1 / 0.651
2pc9 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.650
3hpr AP5Adenylate kinase / 0.650
3ums GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.650
4hdo GNPRas-related protein Rap-1b / 0.650
4x8l AP5Adenylate kinase / 0.650
4x8o AP5Adenylate kinase / 0.650