Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3cd3 STU Tyrosine-protein kinase Fes/Fps 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3cd3 STUTyrosine-protein kinase Fes/Fps 2.7.10.2 1.035
3cbl STUTyrosine-protein kinase Fes/Fps 2.7.10.2 1.023
3bkb STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.986
2j0j 4STFocal adhesion kinase 1 2.7.10.2 0.888
2dq7 STUTyrosine-protein kinase Fyn 2.7.10.2 0.887
1aq1 STUCyclin-dependent kinase 2 2.7.11.22 0.863
2j0m 4STFocal adhesion kinase 1 2.7.10.2 0.855
1pkd UCNCyclin-dependent kinase 2 2.7.11.22 0.853
1u59 STUTyrosine-protein kinase ZAP-70 2.7.10.2 0.813
2yn8 STUEphrin type-B receptor 4 2.7.10.1 0.805
5e8w STUTGF-beta receptor type-1 2.7.11.30 0.790
2nry STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.782
2gcd STUSerine/threonine-protein kinase TAO2 2.7.11.1 0.774
4erw STUCyclin-dependent kinase 2 2.7.11.22 0.772
1nvr STUSerine/threonine-protein kinase Chk1 2.7.11.1 0.768
2z2w 770Wee1-like protein kinase 2.7.10.2 0.767
1snu STUTyrosine-protein kinase ITK/TSK 2.7.10.2 0.765
1sm2 STUTyrosine-protein kinase ITK/TSK 2.7.10.2 0.763
4mvf STUCalcium-dependent protein kinase 2 2.7.11.1 0.761
2hy8 1STSerine/threonine-protein kinase PAK 1 2.7.11.1 0.748
3zew STUEphrin type-B receptor 4 2.7.10.1 0.748
5e8y STUTGF-beta receptor type-2 2.7.11.30 0.747
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
1oky STU3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.743
2clq STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.738
4fr4 STUSerine/threonine-protein kinase 32A 2.7.11.1 0.737
4u97 STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.737
1nvq UCNSerine/threonine-protein kinase Chk1 2.7.11.1 0.736
5e8x STUTGF-beta receptor type-1 2.7.11.30 0.736
4u9a STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.726
4yzc STUSerine/threonine-protein kinase/endoribonuclease IRE1 2.7.11.1 0.725
3bi6 396Wee1-like protein kinase 2.7.10.2 0.724
4qmy STUSerine/threonine-protein kinase 24 2.7.11.1 0.724
1stc STUcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.719
3cr0 809Wee1-like protein kinase 2.7.10.2 0.705
3cqe P91Wee1-like protein kinase 2.7.10.2 0.703
3biz 61EWee1-like protein kinase 2.7.10.2 0.702
1qpj STUTyrosine-protein kinase Lck 2.7.10.2 0.694
1x8b 824Wee1-like protein kinase 2.7.10.2 0.693
2in6 839Wee1-like protein kinase 2.7.10.2 0.693
1xjd STUProtein kinase C theta type 2.7.11.13 0.686
2j0k 4STFocal adhesion kinase 1 2.7.10.2 0.680
2io6 330Wee1-like protein kinase 2.7.10.2 0.679
3a4o STUTyrosine-protein kinase Lyn 2.7.10.2 0.678
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.674
1byg STUTyrosine-protein kinase CSK / 0.673
3d7t STUTyrosine-protein kinase CSK / 0.673
4e4n 0NLTyrosine-protein kinase JAK1 / 0.671
4ccb OFGALK tyrosine kinase receptor 2.7.10.1 0.667
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.665
4e5f 0N7Polymerase acidic protein / 0.660
1nxk STUMAP kinase-activated protein kinase 2 2.7.11.1 0.657
3mtf A3FActivin receptor type-1 2.7.11.30 0.656
2xp2 VGHALK tyrosine kinase receptor 2.7.10.1 0.654
4anq VGHALK tyrosine kinase receptor 2.7.10.1 0.654
3f69 XDRSerine/threonine-protein kinase PknB 2.7.11.1 0.653
4bf2 STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.653
1yvj 4STTyrosine-protein kinase JAK3 2.7.10.2 0.652
2wtj WTJSerine/threonine-protein kinase Chk2 2.7.11.1 0.652
3r9d X6BCyclin-dependent kinase 2 2.7.11.22 0.652