sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 1.171 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.890 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.777 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.727 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.719 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.715 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.713 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.705 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.702 | |
| 2q7i | TES | Androgen receptor | / | 0.701 | |
| 2q7k | TES | Androgen receptor | / | 0.694 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.692 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.692 | |
| 4pxm | EST | Estrogen receptor | / | 0.691 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.690 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.686 | |
| 5l7d | CLR | Smoothened homolog | / | 0.682 | |
| 2yja | EST | Estrogen receptor | / | 0.681 | |
| 3uud | EST | Estrogen receptor | / | 0.677 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.676 | |
| 4hlw | TES | Androgen receptor | / | 0.675 | |
| 1sqn | NDR | Progesterone receptor | / | 0.674 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.674 | |
| 2j7x | EST | Estrogen receptor beta | / | 0.673 | |
| 4k7a | DHT | Androgen receptor | / | 0.672 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.669 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.666 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.662 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.662 | |
| 2qgt | EED | Estrogen receptor | / | 0.659 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.659 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.656 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.656 | |
| 1a50 | FIP | Tryptophan synthase alpha chain | / | 0.650 | |
| 4boe | CLR | Japanin | / | 0.650 |