Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3c7q XIN Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3c7q XINVascular endothelial growth factor receptor 2 2.7.10.1 1.038
2bfy H1NAurora kinase B-A 2.7.11.1 0.707
4qmt H1NSerine/threonine-protein kinase 24 2.7.11.1 0.701
3l9l L9LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.693
4agd B49Vascular endothelial growth factor receptor 2 2.7.10.1 0.691
2pe0 39Z3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.690
3g0e B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.679
4fx3 60KCyclin-dependent kinase 2 2.7.11.22 0.671
2x2m X2MProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.667
2pe1 5173-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.666
3hzt J60Calmodulin-like domain protein kinase isoform 3 / 0.663
2pe2 4643-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.662
3g0f B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.660
1unh IXMCyclin-dependent-like kinase 5 2.7.11.1 0.657
2x2k X2KProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.655
4ft7 H3KSerine/threonine-protein kinase Chk1 2.7.11.1 0.655
1v0o INRCell division control protein 2 homolog 2.7.11.22 0.651
4fkr 45KCyclin-dependent kinase 2 2.7.11.22 0.651
2x81 ZZLAurora kinase A 2.7.11.1 0.650