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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3b8q 900 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3b8q 900Vascular endothelial growth factor receptor 2 2.7.10.1 1.153
3wze BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.803
4asd BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.802
4ase AV9Vascular endothelial growth factor receptor 2 2.7.10.1 0.775
2hzn KINTyrosine-protein kinase ABL1 2.7.10.2 0.770
3b8r 887Vascular endothelial growth factor receptor 2 2.7.10.1 0.717
3rgf BAXCyclin-dependent kinase 8 2.7.11.22 0.717
4agc AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.713
3vhe 42QVascular endothelial growth factor receptor 2 2.7.10.1 0.710
4c8b 0LIReceptor-interacting serine/threonine-protein kinase 2 2.7.11.1 0.706
1uwh BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.705
3tuc FPWTyrosine-protein kinase SYK 2.7.10.2 0.696
2rl5 2RLVascular endothelial growth factor receptor 2 2.7.10.1 0.695
2hz0 GINTyrosine-protein kinase ABL1 2.7.10.2 0.692
2qu6 857Vascular endothelial growth factor receptor 2 2.7.10.1 0.691
4v01 0LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b / 0.685
2xir 00JVascular endothelial growth factor receptor 2 2.7.10.1 0.680
2og8 1N8Tyrosine-protein kinase Lck 2.7.10.2 0.678
3qri 919Tyrosine-protein kinase ABL1 2.7.10.2 0.672
2oh4 GIGVascular endothelial growth factor receptor 2 2.7.10.1 0.668
4fny I3KALK tyrosine kinase receptor 2.7.10.1 0.668
4u0i 0LIMast/stem cell growth factor receptor Kit 2.7.10.1 0.665
3gcs BAXMitogen-activated protein kinase 14 / 0.656
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.652
5amn DTQProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.650