sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.582 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 1.214 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 1.213 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 1.072 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.961 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.947 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.944 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.933 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.915 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.911 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.908 | |
| 2qa1 | FAD | PgaE | / | 0.906 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.891 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.888 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.887 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.885 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.884 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.883 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.882 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.881 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.881 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.880 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.879 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.878 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.876 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.876 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.875 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.874 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.873 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.871 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.869 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.869 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.868 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.867 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.867 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.865 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.865 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.863 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.861 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.860 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.860 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.860 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.859 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.857 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.856 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.855 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.855 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.854 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.852 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.851 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.843 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.843 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.842 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.841 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.840 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.834 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.834 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.833 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.831 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.831 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.830 | |
| 3rha | FDA | Putrescine oxidase | / | 0.830 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.830 | |
| 4jn9 | FAD | DepH | / | 0.830 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.830 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.829 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.828 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.826 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.825 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.825 | |
| 4nte | FAD | DepH | / | 0.825 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.821 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.820 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.820 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.820 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.820 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.820 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.819 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.819 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.818 | |
| 4k5r | FAD | Oxygenase | / | 0.816 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.815 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.814 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.813 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.813 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.812 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.812 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.811 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.810 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.809 | |
| 2bab | FAD | Putative aminooxidase | / | 0.808 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.808 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.808 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.807 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.807 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.807 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.806 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.806 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.804 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.804 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.804 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.801 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.801 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.800 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.799 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.798 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.798 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.798 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.796 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.796 | |
| 4x4j | FAD | Putative oxygenase | / | 0.796 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.796 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.795 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.793 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.793 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.792 | |
| 2bac | FAD | Putative aminooxidase | / | 0.791 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.791 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.790 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.790 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.789 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.789 | |
| 4nev | FAD | Trypanothione reductase | / | 0.788 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.787 | |
| 3fbs | FAD | Oxidoreductase | / | 0.787 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.787 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.786 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.786 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.786 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.786 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.786 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.785 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.785 | |
| 2wow | FAD | Trypanothione reductase | / | 0.785 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.785 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.785 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.785 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.785 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.784 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.782 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.782 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.782 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.782 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.781 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.781 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.781 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.780 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.780 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.780 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.779 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.778 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.778 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.776 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.775 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.774 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.774 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.773 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.773 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.773 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.772 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.770 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.770 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.769 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.768 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.768 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.768 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.768 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.768 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.768 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.768 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.767 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.767 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.767 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.766 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.766 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.764 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.764 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.764 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.763 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.762 | |
| 3fmw | FAD | Oxygenase | / | 0.762 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.761 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.761 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.760 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.760 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.758 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.758 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.758 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.757 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.757 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.757 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.756 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.756 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.755 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.754 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.754 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.754 | |
| 4ysh | FAD | Glycine oxidase | / | 0.754 | |
| 4icy | FAD | PgaE | / | 0.752 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.751 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.751 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.751 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.750 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.750 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.750 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.749 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.748 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.748 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.747 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.747 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.746 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.746 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.746 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.746 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.746 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.745 | |
| 3kkj | FAD | Renalase | / | 0.744 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.743 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.743 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.743 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.742 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.742 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.741 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.741 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.741 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.740 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.740 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.740 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.740 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.739 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.739 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.738 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.737 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.737 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.736 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.736 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.736 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.735 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.735 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.735 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.734 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.733 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.732 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.732 | |
| 4kuk | RBF | Putative blue-light photoreceptor | / | 0.732 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.731 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.731 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.731 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.731 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.730 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.730 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.729 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.729 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.729 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.729 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.728 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.728 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.728 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.728 | |
| 2pd8 | FAD | Vivid PAS protein VVD | / | 0.727 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.727 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.726 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.726 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.725 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.725 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.724 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.723 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.723 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.723 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.723 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.722 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.722 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.722 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.722 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.720 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.720 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.720 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.719 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.719 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.719 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.718 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.718 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.718 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.717 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.716 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.716 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.715 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.715 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.715 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.714 | |
| 5j3w | FMN | Sensory box protein | / | 0.714 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.713 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.713 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.713 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.711 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.711 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.710 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.710 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.709 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.709 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.709 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.709 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.708 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.708 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.707 | |
| 3qj4 | FAD | Renalase | / | 0.707 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.707 | |
| 4tlz | FAD | KtzI | / | 0.707 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.706 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.706 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.705 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.705 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.705 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.705 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.705 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.705 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.704 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.704 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.704 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.703 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.702 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.702 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.702 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.701 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.701 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.700 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.700 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.700 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.699 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.699 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.698 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.698 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.698 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.697 | |
| 3a3b | RBF | Lumazine protein | / | 0.697 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.697 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.696 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.696 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.696 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.695 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.694 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.694 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.694 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.693 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.693 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.693 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.693 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.692 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.692 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.692 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.691 | |
| 3ukk | FDA | UDP-galactopyranose mutase | / | 0.691 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.691 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.691 | |
| 5efw | FMN | NPH1-1 | / | 0.691 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.690 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.690 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.689 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.689 | |
| 3is2 | FAD | Vivid PAS protein VVD | / | 0.689 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.689 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.689 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.688 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.687 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.686 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.686 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.685 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.685 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.684 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.684 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.684 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.683 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.683 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.683 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.683 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.682 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.681 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.680 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.680 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.680 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.680 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.679 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.679 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.678 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.678 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.677 | |
| 3w5u | FAD | Ferredoxin | / | 0.677 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.677 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.676 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.675 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.675 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.675 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.675 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.674 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.674 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.674 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.673 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.673 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.673 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.673 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.672 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.672 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.672 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.672 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.671 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.671 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.671 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.670 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.670 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.669 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.669 | |
| 4ap1 | FAD | Steroid monooxygenase | / | 0.669 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.668 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.668 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.667 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.667 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.667 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.667 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.666 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.666 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.666 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.666 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.665 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.665 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.664 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.664 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.663 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.663 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.663 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.663 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.663 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.663 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.662 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.662 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.661 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.661 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.661 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.660 | |
| 1x0p | FAD | Tll0078 protein | / | 0.660 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.660 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.660 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.659 | |
| 4tm3 | FAD | KtzI | / | 0.659 | |
| 1gaq | FAD | Ferredoxin | / | 0.658 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.658 | |
| 3mzi | FMN | Activator of photopigment and puc expression | / | 0.658 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.657 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.657 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.657 | |
| 4rph | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.657 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.656 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.656 | |
| 3bnk | FMN | Flavoredoxin | / | 0.656 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.655 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.655 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.655 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.655 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.655 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.654 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.653 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.653 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.653 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.653 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.653 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.652 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.652 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.652 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.652 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.651 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.651 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.651 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.651 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.650 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.650 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.650 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.650 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.650 |