Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3a99 ANP Serine/threonine-protein kinase pim-1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3a99 ANPSerine/threonine-protein kinase pim-1 2.7.11.1 0.939
1xr1 ANPSerine/threonine-protein kinase pim-1 2.7.11.1 0.754
1lp4 ANPCasein kinase II subunit alpha 2.7.11.1 0.731
2pun ACPMethylthioribose kinase 2.7.1.100 0.717
2pul ACPMethylthioribose kinase 2.7.1.100 0.716
2olc ADPMethylthioribose kinase 2.7.1.100 0.715
4ifc ADPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.710
2b9f ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.705
4xlv ACPInsulin receptor 2.7.10.1 0.703
5cvf ATPCasein kinase II subunit alpha 2.7.11.1 0.703
4fl1 ANPTyrosine-protein kinase SYK 2.7.10.2 0.702
2pui ADPMethylthioribose kinase 2.7.1.100 0.701
1daw ANPCasein kinase II subunit alpha 2.7.11.1 0.699
2b9j ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.699
3nsz ANPCasein kinase II subunit alpha 2.7.11.1 0.698
1zth ADPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.697
3dqw AGSProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.695
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.694
1jkl ANPDeath-associated protein kinase 1 2.7.11.1 0.693
4ii5 ADPCyclin-dependent kinase 2 2.7.11.22 0.693
1o6y ACPSerine/threonine-protein kinase PknB 2.7.11.1 0.691
3gu7 ADPDeath-associated protein kinase 1 2.7.11.1 0.690
1j1c ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.688
2b9i ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.688
4jqe ANPCasein kinase II subunit alpha 2.7.11.1 0.688
1zp9 ATPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.686
5awm ANPStress-activated protein kinase JNK 2.7.11.24 0.686
4f9a ADPCell division cycle 7-related protein kinase 2.7.11.1 0.685
1w2d ADPInositol-trisphosphate 3-kinase A 2.7.1.127 0.684
4qny ANPMitogen activated protein kinase, putative / 0.683
4iir ANPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.681
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.680
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.680
3a7h ATPSerine/threonine-protein kinase 24 2.7.11.1 0.675
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.675
3gu4 ANPDeath-associated protein kinase 1 2.7.11.1 0.673
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.673
4y0x ADPSerine/threonine-protein kinase PknG 2.7.11.1 0.668
1m0w ANPGlutathione synthetase 6.3.2.3 0.667
2a19 ANPInterferon-induced, double-stranded RNA-activated protein kinase 2.7.11.1 0.666
4k33 ACPFibroblast growth factor receptor 3 2.7.10.1 0.666
4dee ADPAurora kinase A 2.7.11.1 0.665
4h3q ANPMitogen-activated protein kinase 1 2.7.11.24 0.665
1j1b ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.664
4q5j ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.663
4ux9 ANPMitogen-activated protein kinase 8 2.7.11.24 0.663
3att ATPPutative aminoglycoside phosphotransferase 2.7.1 0.662
1mq4 ADPAurora kinase A 2.7.11.1 0.661
3llt ANPProtein serine/threonine kinase-1 / 0.661
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.661
4iaz ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.661
4aqk ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.660
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.659
1pjk ANPCasein kinase II subunit alpha 2.7.11.1 0.658
4axf ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.658
1ol6 ATPAurora kinase A 2.7.11.1 0.656
4q5h ANPProtein kinase OspG 2.7 0.656
4f99 ADPCell division cycle 7-related protein kinase 2.7.11.1 0.655
4fmq ANPMitogen-activated protein kinase 1 2.7.11.24 0.655
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.653
5dt4 ATPAurora kinase A 2.7.11.1 0.653
2w4j ADPDeath-associated protein kinase 1 2.7.11.1 0.652
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.652
3o0o TTPVitamin B12-dependent ribonucleotide reductase / 0.652
4gvj ADPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.652
1qmz ATPCyclin-dependent kinase 2 2.7.11.22 0.651
4r8q ADPMitotic checkpoint serine/threonine-protein kinase BUB1 2.7.11.1 0.651
4aw1 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.650
4wbb ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.650