sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.243 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.111 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 1.091 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 1.081 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 1.026 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.968 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.963 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.962 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.960 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.952 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.944 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.932 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.911 | |
| 4kwh | NAP | Reductase homolog | / | 0.909 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.909 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.903 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.901 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.898 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.897 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.884 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.883 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.877 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.876 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.874 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.873 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.869 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.865 | |
| 3uce | NDP | Dehydrogenase | / | 0.859 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.858 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.855 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.854 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.854 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.853 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.852 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.850 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.848 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.843 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.843 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.843 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.840 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.839 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.838 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.836 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.835 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.835 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.832 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.831 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.827 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.826 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.822 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.822 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.820 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.819 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.819 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.818 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.818 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.818 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.817 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.817 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.814 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.812 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.811 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.809 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.806 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.804 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.803 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.802 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.802 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.801 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.801 | |
| 1sny | NAP | LD36273p | / | 0.800 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.800 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.800 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.796 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.795 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.795 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.794 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.793 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.792 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.791 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.791 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.787 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.786 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.785 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.784 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.784 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.783 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.782 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.780 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.777 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.777 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.775 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.775 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.773 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.772 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.771 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.768 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.766 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.765 | |
| 4qec | NAP | ElxO | / | 0.765 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.764 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.763 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.763 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.761 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.756 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.756 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.756 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.755 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.754 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.754 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.754 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.753 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.750 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.750 | |
| 4clo | NAP | Pteridine reductase | / | 0.750 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.749 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.748 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.748 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.747 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.745 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.745 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.744 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.741 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.739 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.739 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.739 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.738 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.737 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.737 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.735 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.735 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.735 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.734 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.733 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.733 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.732 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.732 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.732 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.728 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.725 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.725 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.725 | |
| 5d2e | NAP | MlnE | / | 0.725 | |
| 1iy8 | NAD | Levodione reductase | / | 0.724 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.724 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.721 | |
| 4qed | NAP | ElxO | / | 0.721 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.720 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.719 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.719 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.715 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.714 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.714 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.714 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.713 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.712 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.712 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.711 | |
| 4u7w | NDP | MxaA | / | 0.711 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.710 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.710 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.710 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.709 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.709 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.707 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.707 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.707 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.706 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.705 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.704 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.703 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.703 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.701 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.700 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.699 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.698 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.698 | |
| 3bmo | NAP | Pteridine reductase | / | 0.698 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.697 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 3sju | NDP | Keto reductase | / | 0.696 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.694 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.692 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.691 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 3mje | NDP | AmphB | / | 0.689 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.687 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.684 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.683 | |
| 4hxy | NDP | Plm1 | / | 0.682 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.681 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.680 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.679 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.678 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.678 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.678 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.676 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.675 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.673 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.672 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.672 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.672 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.671 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.671 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.670 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.668 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.668 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.666 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.666 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.665 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.665 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.664 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.663 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.662 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.662 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 4ros | APR | Malate dehydrogenase | / | 0.662 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.660 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.660 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.660 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.660 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.660 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.659 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.659 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.657 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.657 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.657 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.656 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.655 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.654 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.654 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.654 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.652 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.652 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.651 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.651 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.650 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.650 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.650 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.650 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.650 |