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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zdt 46C Mitogen-activated protein kinase 10 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2zdt 46CMitogen-activated protein kinase 10 2.7.11.24 1.230
2zdu 446Mitogen-activated protein kinase 10 2.7.11.24 0.895
4g1w G1WMitogen-activated protein kinase 8 2.7.11.24 0.802
3g9n J88Mitogen-activated protein kinase 10 2.7.11.24 0.692
2obj VRVSerine/threonine-protein kinase pim-1 2.7.11.1 0.668
2x23 TCUEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.656
1krv 147Galactoside O-acetyltransferase 2.3.1.18 0.654
3iw8 HIZMitogen-activated protein kinase 14 / 0.654
3vs2 VSBTyrosine-protein kinase HCK 2.7.10.2 0.654
3c4e C4ESerine/threonine-protein kinase pim-1 2.7.11.1 0.652
4afj SJJGlycogen synthase kinase-3 beta 2.7.11.26 0.652
3qqg X06Cyclin-dependent kinase 2 2.7.11.22 0.651
4c57 FEFCyclin-G-associated kinase 2.7.11.1 0.650