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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2zbp SAM Ribosomal protein L11 methyltransferase 2.1.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2zbp SAMRibosomal protein L11 methyltransferase 2.1.1 0.925
3cjq SAHRibosomal protein L11 methyltransferase 2.1.1 0.775
3cjt SAHRibosomal protein L11 methyltransferase 2.1.1 0.775
3egv SAHRibosomal protein L11 methyltransferase 2.1.1 0.757
2nxe SAMRibosomal protein L11 methyltransferase 2.1.1 0.724
1nw3 SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.706
4gek GEKCarboxy-S-adenosyl-L-methionine synthase / 0.694
4lwp SAHArginine N-methyltransferase, putative / 0.693
1kia SAMGlycine N-methyltransferase 2.1.1.20 0.688
3lcc SAHThiocyanate methyltransferase 1 / 0.685
2h00 SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase / 0.684
3sr4 TT8Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.684
4qpp SAHProtein arginine N-methyltransferase 6 / 0.682
3b3f SAHHistone-arginine methyltransferase CARM1 / 0.672
4iwn GEKCarboxy-S-adenosyl-L-methionine synthase / 0.659
3iei SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.657
5dxa SFGHistone-arginine methyltransferase CARM1 / 0.657
5jdz SAHMethyl transferase / 0.657
5dx1 SFGHistone-arginine methyltransferase CARM1 / 0.656
1rjd SAMLeucine carboxyl methyltransferase 1 2.1.1.233 0.653
5ccb SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.653
2bh2 SAH23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD / 0.652
2vdv SAMtRNA (guanine-N(7)-)-methyltransferase / 0.651
1vq1 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.650
4dmg SAMUncharacterized protein / 0.650
5je2 SAHMethyl transferase / 0.650