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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2z7h GG3 Geranylgeranyl pyrophosphate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2z7h GG3Geranylgeranyl pyrophosphate synthase / 1.131
2e91 ZOLGeranylgeranyl pyrophosphate synthase / 0.824
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.800
2z4w 749Geranylgeranyl pyrophosphate synthase / 0.735
2zev B71Geranylgeranyl pyrophosphate synthase / 0.735
3icz PB6Farnesyl pyrophosphate synthase / 0.714
2bc9 GNPGuanylate-binding protein 1 / 0.689
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.686
2z4z SC0Geranylgeranyl pyrophosphate synthase / 0.673
5dha GNPGTP-binding nuclear protein Ran / 0.667
5ero 210Fusicoccadiene synthase 2.5.1.29 0.659
5di3 GNPADP-ribosylation factor-like protein 3 / 0.652