Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ym6 YM6 Serine/threonine-protein kinase Chk1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ym6 YM6Serine/threonine-protein kinase Chk1 2.7.11.1 0.906
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2wmv ZYVSerine/threonine-protein kinase Chk1 2.7.11.1 0.697
2ym3 YM3Serine/threonine-protein kinase Chk1 2.7.11.1 0.688
3mvj XFEcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.686
2ym4 4YMSerine/threonine-protein kinase Chk1 2.7.11.1 0.675
3nuu JOZ3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.670
4utd ACPAurora kinase A 2.7.11.1 0.661
4oti MI1Serine/threonine-protein kinase N1 / 0.659
2gdo 12CSerine/threonine-protein kinase Chk1 2.7.11.1 0.656
3qcq 3Q03-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.656
3zo1 SIJcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.655
1jpa ANPEphrin type-B receptor 2 2.7.10.1 0.654
2pzr ACPFibroblast growth factor receptor 2 / 0.654
3r02 UNMSerine/threonine-protein kinase pim-1 2.7.11.1 0.654
2pe0 39Z3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.653
2x2m X2MProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.653
4ks8 B49Serine/threonine-protein kinase PAK 6 2.7.11.1 0.653
3uix Q17Serine/threonine-protein kinase pim-1 2.7.11.1 0.651
4yuq KS1Calmodulin-like domain protein kinase / 0.651