Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yjz NAP Metalloreductase STEAP4 1.16.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2yjz NAPMetalloreductase STEAP4 1.16.1 1.088
2vq3 NAPMetalloreductase STEAP3 / 0.782
2qw8 NAPEugenol synthase 1 1.1.1.318 0.772
2r6j NDPEugenol synthase 1 1.1.1.318 0.741
2qx7 NAPEugenol synthase 1 1.1.1.318 0.715
3c3x NAPEugenol synthase 1 1.1.1.318 0.702
1o8c NDPProbable acrylyl-CoA reductase AcuI 1.3.1.84 0.694
4b4o NDPEpimerase family protein SDR39U1 / 0.694
5a05 NDPGlucose-fructose oxidoreductase / 0.693
1yqd NAPSinapyl alcohol dehydrogenase / 0.691
1zh8 NAPUncharacterized protein / 0.687
2c29 NAPDihydroflavonol 4-reductase / 0.687
2ixb NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.682
3rku NAPNADP-dependent 3-hydroxy acid dehydrogenase / 0.681
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.680
5ein NAP[LysW]-L-2-aminoadipate 6-phosphate reductase / 0.680
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.678
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.678
4hwk NAPSepiapterin reductase 1.1.1.153 0.678
3uce NDPDehydrogenase / 0.677
5a02 NAPGlucose-fructose oxidoreductase / 0.677
4c7k NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.675
5a03 NDPGlucose-fructose oxidoreductase / 0.675
1oaa NAPSepiapterin reductase 1.1.1.153 0.673
1qr6 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.672
3phi NDPShikimate dehydrogenase (NADP(+)) / 0.672
5a04 NDPGlucose-fructose oxidoreductase / 0.672
4wji NAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase / 0.670
1x7h NDPPutative ketoacyl reductase 1.3.1 0.669
2jah NDPClavaldehyde dehydrogenase / 0.669
2yut NAPPutative short-chain oxidoreductase / 0.668
3p19 NDPPutative blue fluorescent protein / 0.668
4y1b NAPAntE / 0.668
3tri NAPPyrroline-5-carboxylate reductase / 0.664
1piw NAPNADP-dependent alcohol dehydrogenase 6 1.1.1.2 0.663
4z3d NDPCarbonyl reductase [NADPH] 1 1.1.1.184 0.663
3wbb NAPMeso-diaminopimelate D-dehydrogenase / 0.661
4nd2 A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.661
3ics COACoenzyme A disulfide reductase / 0.658
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.658
4xb2 NDP319aa long hypothetical homoserine dehydrogenase / 0.658
3mvq NDPGlutamate dehydrogenase 1, mitochondrial 1.4.1.3 0.657
4k28 NADShikimate dehydrogenase family protein / 0.657
4j7u NAPSepiapterin reductase 1.1.1.153 0.656
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.655
3h3j NADL-lactate dehydrogenase 1 1.1.1.27 0.654
5eio NAP[LysW]-L-2-aminoadipate 6-phosphate reductase / 0.653
4hxy NDPPlm1 / 0.652
5bsf NADPyrroline-5-carboxylate reductase / 0.652
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.651
3wbf NAPMeso-diaminopimelate D-dehydrogenase / 0.650