Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yis YIS Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2yis YISMitogen-activated protein kinase 14 / 1.449
2yiw YIWMitogen-activated protein kinase 14 / 1.171
3hv7 1AUMitogen-activated protein kinase 14 / 0.952
2puu G2GMitogen-activated protein kinase 14 / 0.929
3p7b P7BMitogen-activated protein kinase 14 / 0.923
3nnw EDDMitogen-activated protein kinase 14 / 0.889
3p5k P5KMitogen-activated protein kinase 14 / 0.882
3hv6 R39Mitogen-activated protein kinase 14 / 0.873
3nnx EDDMitogen-activated protein kinase 14 / 0.864
1kv2 B96Mitogen-activated protein kinase 14 / 0.843
3npc B96Mitogen-activated protein kinase 9 2.7.11.24 0.840
3hv3 R49Mitogen-activated protein kinase 14 / 0.832
1w82 L10Mitogen-activated protein kinase 14 / 0.828
3p7c P7CMitogen-activated protein kinase 14 / 0.810
3uvr 06FMitogen-activated protein kinase 14 / 0.777
4f7j 0SUCyclin-dependent kinase 8 2.7.11.22 0.766
4f6s 0SQCyclin-dependent kinase 8 2.7.11.22 0.764
3lfb Z87Mitogen-activated protein kinase 14 / 0.759
4f6w 0SSCyclin-dependent kinase 8 2.7.11.22 0.756
4k9y K9YFocal adhesion kinase 1 2.7.10.2 0.754
4kao KAOFocal adhesion kinase 1 2.7.10.2 0.752
2yix YIXMitogen-activated protein kinase 14 / 0.750
4f7n 0SVCyclin-dependent kinase 8 2.7.11.22 0.747
3hv4 L51Mitogen-activated protein kinase 14 / 0.739
3p7a P7AMitogen-activated protein kinase 14 / 0.735
3gi3 B10Mitogen-activated protein kinase 14 / 0.734
3hv5 R24Mitogen-activated protein kinase 14 / 0.729
4eyj N61Mitogen-activated protein kinase 13 2.7.11.24 0.729
4f7l 0SOCyclin-dependent kinase 8 2.7.11.22 0.729
3qri 919Tyrosine-protein kinase ABL1 2.7.10.2 0.727
3gcv SS6Mitogen-activated protein kinase 14 / 0.721
3nww 3NWMitogen-activated protein kinase 14 / 0.716
3lfe Z84Mitogen-activated protein kinase 14 / 0.715
3gcq 1BUMitogen-activated protein kinase 14 / 0.706
3o8t BMUMitogen-activated protein kinase 14 / 0.704
3o8u BMUMitogen-activated protein kinase 14 / 0.704
3gcu R48Mitogen-activated protein kinase 14 / 0.689
3p79 P79Mitogen-activated protein kinase 14 / 0.688
1ove 358Mitogen-activated protein kinase 14 / 0.684
3oc1 BMUMitogen-activated protein kinase 14 / 0.681
3lff Z83Mitogen-activated protein kinase 14 / 0.675
4c8b 0LIReceptor-interacting serine/threonine-protein kinase 2 2.7.11.1 0.674
4h1m 0YJProtein-tyrosine kinase 2-beta 2.7.10.2 0.674
3vhe 42QVascular endothelial growth factor receptor 2 2.7.10.1 0.672
4asd BAXVascular endothelial growth factor receptor 2 2.7.10.1 0.671
4twn B96Ephrin type-A receptor 3 2.7.10.1 0.668
3pg3 DG7Mitogen-activated protein kinase 14 / 0.666
2oh4 GIGVascular endothelial growth factor receptor 2 2.7.10.1 0.663
2hzn KINTyrosine-protein kinase ABL1 2.7.10.2 0.662
3p78 P78Mitogen-activated protein kinase 14 / 0.661
3gcs BAXMitogen-activated protein kinase 14 / 0.659
4f70 0STCyclin-dependent kinase 8 2.7.11.22 0.659
1kv1 BMUMitogen-activated protein kinase 14 / 0.656
4h1j 0YHProtein-tyrosine kinase 2-beta 2.7.10.2 0.654
3rgf BAXCyclin-dependent kinase 8 2.7.11.22 0.653
1w83 L11Mitogen-activated protein kinase 14 / 0.650