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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2xyu Q9G Ephrin type-A receptor 4 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2xyu Q9GEphrin type-A receptor 4 2.7.10.1 1.019
4g2f C07Ephrin type-A receptor 3 2.7.10.1 0.686
1wzy F29Mitogen-activated protein kinase 1 2.7.11.24 0.676
3rin I2OMitogen-activated protein kinase 14 / 0.673
2zyb KSLTyrosine-protein kinase Lck 2.7.10.2 0.666
4gk2 L66Ephrin type-A receptor 3 2.7.10.1 0.665
2zva 1N1Tyrosine-protein kinase Lyn 2.7.10.2 0.664
2vwu 7X1Ephrin type-B receptor 4 2.7.10.1 0.653
3bi6 396Wee1-like protein kinase 2.7.10.2 0.652
3fsf FSSMitogen-activated protein kinase 14 / 0.650